TOX2 Antibody, Biotin conjugated

說明書

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) TOX2 Polyclonal antibody
Uniprot No.：

Q96NM4
基因名：

TOX2
別名：

C20orf100 antibody; Chromosome 20 open reading frame 100 antibody; dJ1108D11.2 antibody; dJ495O3.1 antibody; GCX 1 antibody; GCX1 antibody; Granulosa cell HMG box protein 1 antibody; MGC15880 antibody; TOX high mobility group box family member 2 antibody; TOX2 antibody; TOX2_HUMAN antibody; Weakly similar to NONHISTONE CHROMOSOMAL PROTEIN 6A [S.cerevisiae] antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human TOX high mobility group box family member 2 protein (303-417AA)
免疫原種屬：

Homo sapiens (Human)
標記方式：

Biotin
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Putative transcriptional activator involved in the hypothalamo-pituitary-gonadal system.
基因功能參考文獻：
1. A haplotype block across a 24-kb region within the TOX2 gene reached genome-wide significance in haplotype-block-based regional heritability mapping. Single-SNP- and haplotype-based association tests demonstrated that five of nine genotyped SNPs and two haplotypes within this block were significantly associated with major depressive disorder. PMID: 28153336
2. TOX2 plays a crucial role in controlling normal NK cell development by acting upstream of TBX21 transcriptional regulation PMID: 25352127
3. A novel aberrantly hypermethylated CpG island in cancer was discovered within the TOX2 promoter. TOX2 was unmethylated in normal cells. Expression of two novel TOX2 transcripts was significantly reduced in primary lung tumors. PMID: 22496870
4. Identification and functional analysis of the rat Gcx1 ortholog. PMID: 14764631
亞細胞定位：

Nucleus.
數據庫鏈接：

HGNC: 16095

OMIM: 611163

KEGG: hsa:84969

UniGene: Hs.26608

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