TNMD Antibody, FITC conjugated
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中文名稱：TNMD兔多克隆抗體, FITC偶聯
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貨號：CSB-PA024007LC01HU
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規格：￥880
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) TNMD Polyclonal antibody
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Uniprot No.：
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基因名：TNMD
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別名：BRICD4 antibody; BRICHOS domain containing 4 antibody; CHM1 LIKE antibody; ChM1L antibody; Chondromodulin I like antibody; Chondromodulin I like protein antibody; Chondromodulin-1-like protein antibody; Chondromodulin-I-like protein antibody; hChM1L antibody; hTeM antibody; Myodulin antibody; TeM antibody; Tendin antibody; Tenomodulin antibody; Tenomodulin protein antibody; Tnmd antibody; TNMD_HUMAN antibody; UNQ771/PRO1565 antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Recombinant Human Tenomodulin protein (131-254AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：FITC
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 -
產品提供形式：Liquid
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
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靶點詳情
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功能：May be an angiogenesis inhibitor.
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基因功能參考文獻：
- our study demonstrates that Tnmd is required for proper tendon tissue adaptation to endurance running and aids in better understanding of the structural-functional relationships of tendon tissues. PMID: 28566251
- TNMD is upregulated in adipose tissue of insulin-resistant versus insulin-sensitive individuals. TNMD expression increases in human preadipocytes during differentiation, whereas silencing TNMD blocks adipogenesis. PMID: 26880110
- results suggest that Tnmd acts on the maturation or maintenance of the PDL by positively regulating cell adhesion via its BRICHOS domain PMID: 23593173
- Report differential expression and cellular localization of novel isoforms of the tendon biomarker tenomodulin and suggest possible roles in tenocyte proliferation and tendon injury. PMID: 22700804
- According to these results the sequence variation of TNMD is not associated with alzheimer disease, but might modify the effect of APOE epsilon4-allele in women. PMID: 19524323
- Polymorphisms are associated with adiposity and also with glucose metabolism and conversion from glucose intolerance to type 2 diabetes. PMID: 17495183
- Tenomodulin is expressed abundantly in the elastin-rich subendothelial outer layer of the normal chordae tendineae cordis. PMID: 18838562
- TNMD could be a novel candidate gene for age-related macular degeneration. PMID: 19381347
- Human adipose tissue TNMD gene expression is highly affected by obesity, adipose tissue location, and weight loss, indicating that TNMD may play a role in adipose tissue function. PMID: 19602561
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亞細胞定位：[Isoform 1]: Membrane; Single-pass type II membrane protein. Nucleus envelope.; [Isoform 2]: Membrane; Single-pass type II membrane protein. Nucleus envelope.; [Isoform 3]: Cytoplasm.
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蛋白家族：Chondromodulin-1 family
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組織特異性：Highly expressed in hypovascular connective tissues such as tendons. Has also strong expression in adipose tissue.
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數據庫鏈接：
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