TNFRSF19 Antibody

中文名稱：

TNFRSF19兔多克隆抗體
貨號：

CSB-PA878878LA01HU
規格：

￥440
圖片：
Western Blot
Positive WB detected in: PC-3 whole cell lysate
All lanes: TNFRSF19 antibody at 2.36μg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 47, 46, 31 kDa
Observed band size: 47 kDa

Immunofluorescence staining of HepG2 cells with CSB-PA878878LA01HU at 1:200, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
其他：

產品詳情
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靶點詳情

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) TNFRSF19 Polyclonal antibody
Uniprot No.：

Q9NS68
基因名：

TNFRSF19
別名：

AL023044 antibody; AW123854 antibody; TAJ alpha antibody; TAJ antibody; TAJ-alpha antibody; TNFRSF19 antibody; TNFRSF19 tumor necrosis factor receptor superfamily, member 19 antibody; TNR19_HUMAN antibody; Toxicity and JNK inducer antibody; TRADE antibody; TROY antibody; Tumor necrosis factor receptor superfamily member 19 antibody; UNQ1888/PRO4333 antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Tumor necrosis factor receptor superfamily member 19 protein (276-415AA)
免疫原種屬：

Homo sapiens (Human)

標記方式：

Non-conjugated

本頁面中的產品，TNFRSF19 Antibody (CSB-PA878878LA01HU)，的標記方式是Non-conjugated。對于TNFRSF19 Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA878878LB01HU	TNFRSF19 Antibody, HRP conjugated	ELISA
FITC	CSB-PA878878LC01HU	TNFRSF19 Antibody, FITC conjugated
Biotin	CSB-PA878878LD01HU	TNFRSF19 Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA, WB, IF

推薦稀釋比：

Application	Recommended Dilution
WB	1:500-1:5000
IF	1:50-1:200

Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
Immunofluorescence (IF) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

功能：

Can mediate activation of JNK and NF-kappa-B. May promote caspase-independent cell death.
基因功能參考文獻：
1. TNFRSF19 may contribute to the development of colorectal tumors with deregulated beta-catenin activity. PMID: 24623448
2. Results show aberrant expression and/or signaling by TROY as a contributor to the dispersion of glioblastoma cells and therapeutic resistance. PMID: 23699535
3. the association of RhoGDIalpha with TROY contributed to TROY-dependent RhoA activation and neurite outgrowth inhibition after Nogo-66 stimulation. PMID: 24129566
4. TROY is up-regulated in human colorectal cancer cell lines and in intestinal tumors in mice. It functions as a negative modulator of the Wnt pathway in LGR5-positive stem cells. PMID: 23142137
5. study demonstrated that TNFR2 and TROY mRNA levels are enhanced in cutaneous squamous cell carcinoma cells compared to healthy ones in a Tunisian population PMID: 22057614
6. TNFRSF19 overexpression in glioma cells activates Rac1 signaling in a Pyk2-dependent manner to drive glioma cell invasion and migration PMID: 20881009
7. Findings provide new insights into the pathogenesis of NPC by highlighting the involvement of pathways related to TNFRSF19 and MDS1-EVI1 in addition to HLA molecules. PMID: 20512145
8. TROY regulates melanoma growth. PMID: 17187358
9. the ternary complex of NgR/TROY/LINGO-1 expressed on astrocytes, macrophages/microglia and neurones, by interacting with Nogo-A on oligodendrocytes, might modulate glial-neuronal interactions in demyelinating lesions of multiple sclerosis PMID: 17239012
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亞細胞定位：

Membrane; Single-pass type I membrane protein.
組織特異性：

Highly expressed in prostate. Detected at lower levels in thymus, spleen, testis, uterus, small intestine, colon and peripheral blood leukocytes.
數據庫鏈接：

HGNC: 11915

OMIM: 606122

KEGG: hsa:55504

STRING: 9606.ENSP00000371693

UniGene: Hs.149168

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