TMEM98 Antibody

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) TMEM98 Polyclonal antibody
Uniprot No.：

Q9Y2Y6
基因名：

TMEM98
別名：

TMEM98 antibody; UNQ536/PRO1079 antibody; Transmembrane protein 98 antibody; Protein TADA1 antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Transmembrane protein 98 protein (25-226AA)
免疫原種屬：

Homo sapiens (Human)

標記方式：

Non-conjugated

本頁面中的產品，TMEM98 Antibody (CSB-PA023901LA01HU)，的標記方式是Non-conjugated。對于TMEM98 Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA023901LB01HU	TMEM98 Antibody, HRP conjugated	ELISA
FITC	CSB-PA023901LC01HU	TMEM98 Antibody, FITC conjugated
Biotin	CSB-PA023901LD01HU	TMEM98 Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Functions as a negative regulator of MYRF in oligodendrocyte differentiation and myelination. Interacts with the C-terminal of MYRF inhibiting MYRF self-cleavage and N-fragment nuclear translocation. The secreted form promotes differentiation of T helper 1 cells (Th1).
基因功能參考文獻：
1. siRNA-TMEM98 inhibited the invasion and migration of non-small cell lung cancer cells. PMID: 26884835
2. Two novel TMEM98 mutations have been found in two pedigrees with autosomal dominant nanophthalmos. PMID: 26392740
3. we identified a panel of novel common chemoresistance-associated genes and demonstrated that TMEM98 is a chemoresistance-conferring gene in hepatocellular carcinoma. PMID: 24608572
4. A novel gene associated with nanophthalmos, TMEM98 most likely represents the cause of the disease. PMID: 24852644
相關疾病：

Nanophthalmos 4 (NNO4)
亞細胞定位：

Cell membrane; Single-pass type II membrane protein. Secreted. Secreted, extracellular exosome. Endoplasmic reticulum membrane; Single-pass type II membrane protein.
蛋白家族：

TMEM98 family
組織特異性：

Widely expressed with high expression in the ovary, pancreas and prostate. Expressed in the eye, particularly in corneal endothelium, iris, ciliary body, sclera, optic nerve, optic nerve head, and retina. Expressed by activated peripheral blood mononuclea
數據庫鏈接：

HGNC: 24529

OMIM: 615949

KEGG: hsa:26022

STRING: 9606.ENSP00000378138

UniGene: Hs.3447

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