TM7SF2 Antibody

說明書

中文名稱：

TM7SF2兔多克隆抗體
貨號：

CSB-PA275949
規格：

￥1100
圖片：
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA275949(TM7SF2 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200)

Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Human fetal brain tissue, Primary antibody: CSB-PA275949(TM7SF2 Antibody) at dilution 1/500, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute
其他：

產品詳情

Uniprot No.：

O76062
基因名：

TM7SF2
別名：

TM7SF2; ANG1; Delta(14-sterol reductase TM7SF2; Delta-14-SR; 3-beta-hydroxysterol Delta; 14-reductase; Another new gene 1 protein; C-14 sterol reductase; C14SR; Putative sterol reductase SR-1; Sterol C14-reductase; Transmembrane 7 superfamily member 2
宿主：

Rabbit
反應種屬：

Human,Mouse
免疫原：

Synthetic peptide of Human TM7SF2
免疫原種屬：

Homo sapiens (Human)
標記方式：

Non-conjugated
抗體亞型：

IgG
純化方式：

Antigen affinity purification
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
產品提供形式：

Liquid
應用范圍：

ELISA,WB,IHC

推薦稀釋比：

Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
Immunohistochemistry (IHC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Catalyzes the reduction of the C14-unsaturated bond of lanosterol, as part of the metabolic pathway leading to cholesterol biosynthesis.
基因功能參考文獻：
1. LBR mutant variants and sterol reductases can severely interfere with the regular organization of the nuclear envelope and the endoplasmic reticulum. PMID: 19940018
2. Results show that the TM7SF2 gene product SR-1 and six chimeras containing SR-1 and Neurospora erg-3 sequences fail to complement sterol c-14 reductase mutants in Neurospora and yeast. PMID: 11937680
3. a primary role in human cholesterol biosynthesis PMID: 16784888
亞細胞定位：

Microsome membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
蛋白家族：

ERG4/ERG24 family
組織特異性：

Expressed in adult heart, brain, pancreas, lung, liver, skeletal muscle, kidney, ovary, prostate, testis and adrenal gland, but not detected in placenta, spleen, thymus, small intestine, colon (mucosal lining), or peripheral blood leukocytes.
數據庫鏈接：

HGNC: 11863

OMIM: 603414

KEGG: hsa:7108

STRING: 9606.ENSP00000279263

UniGene: Hs.31130

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