THSD1 Antibody
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中文名稱：THSD1兔多克隆抗體
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貨號：CSB-PA776650
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規格：￥1100
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圖片：
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The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA776650(THSD1 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: ×200)
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其他：
產品詳情
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Uniprot No.：
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基因名：THSD1
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別名：4833423O18Rik antibody; MGC74971 antibody; Thrombospondin type 1 domain containing protein 1 antibody; Thrombospondin type I domain 1 antibody; Thrombospondin type-1 domain-containing protein 1 antibody; Thrombospondin, type I, domain containing 1 antibody; THSD1 antibody; THSD1_HUMAN antibody; TMTSP antibody; Transmembrane molecule with thrombospondin module antibody; UNQ3010 antibody
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宿主：Rabbit
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反應種屬：Human,Mouse
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免疫原：Fusion protein of Human THSD1
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
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抗體亞型：IgG
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純化方式：Antigen affinity purification
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
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產品提供形式：Liquid
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應用范圍：ELISA,IHC
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推薦稀釋比：
Application Recommended Dilution ELISA 1:2000-1:5000 IHC 1:25-1:100 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Is a positive regulator of nascent focal adhesion assembly, involved in the modulation of endothelial cell attachment to the extracellular matrix.
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基因功能參考文獻：
- THSD1 forms a multimeric protein complex with FAK/talin/vinculin, wherein THSD1 promotes talin binding to FAK but not to vinculin, a key step in nascent adhesion assembly. PMID: 29069646
- THSD1 mutation associated with Intracranial Aneurysm and Subarachnoid Hemorrhage. PMID: 27895300
- thrombospondin type I domain 1 is a new regulator of endothelial barrier function during vascular development and protects intraplaque microvessels against haemorrhaging in advanced atherosclerotic lesions PMID: 26822228
- The THSD1 gene may play a role in the tumorigenesis of colorectal cancer PMID: 22664866
- Thrombospondin has a role in inducing RhoA inactivation through FAK-dependent signaling to stimulate focal adhesion disassembly PMID: 15371459
- The strong immunolocalization of thrombospondin (TSP) in the outer anulus of the intervertebral disc indicates a role for TSP in the avascular status of the adult human disc. PMID: 17047544
- These findings suggest that THSD1 is a good candidate tumor suppressor gene. PMID: 18403638
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亞細胞定位：[Isoform 1]: Endosome membrane; Single-pass type I membrane protein. Cell junction, focal adhesion.; [Isoform 2]: Membrane; Single-pass type I membrane protein.; [Isoform 3]: Secreted.
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