TGIF2 Antibody, FITC conjugated
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中文名稱：TGIF2兔多克隆抗體, FITC偶聯
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貨號：CSB-PA884421LC01HU
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規格：￥880
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) TGIF2 Polyclonal antibody
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Uniprot No.：
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基因名：
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別名：5' TG 3' interacting factor 2 antibody; 5''-TG-3''-interacting factor 2 antibody; Homeobox protein TGIF2 antibody; TGF (beta) induced transcription factor 2 antibody; TGF beta induced factor 2 antibody; TGF-beta-induced transcription factor 2 antibody; TGFB induced factor 2 antibody; TGFB-induced factor 2 antibody; Tgif2 antibody; TGIF2_HUMAN antibody; Transforming growth factor beta induced factor 2 antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Recombinant Human Homeobox protein TGIF2 protein (82-222AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：FITC
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 -
產品提供形式：Liquid
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
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靶點詳情
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功能：Transcriptional repressor, which probably repress transcription by binding directly the 5'-CTGTCAA-3' DNA sequence or by interacting with TGF-beta activated SMAD proteins. Probably represses transcription via the recruitment of histone deacetylase proteins.
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基因功能參考文獻：
- Tgifs regulate ciliogenesis and suggests that Evi5l mediates at least part of this effect. PMID: 27956704
- Authors suggest that miR-148a inhibits OC cell proliferation and invasion partly through inhibition of TGFI2. Therefore, this study highlights the importance of the miR-148a/TGFI2 axis in the malignant progression of OC. PMID: 27712592
- Data show that TGFB-induced factor 2 protein (TGIF2) is involved in microRNA miR-541-3p-regulated cell proliferation, invasion, migration, as well as cell cycle of non-small lung cancer (NSCLC) cells. PMID: 27448300
- expression of miR-148a was regulated by DNA methylation and targeted by TGIF2. Its methylation may be a potential prognostic indicator in skin cancer PMID: 26638007
- miR-34a could inhibit tumor invasion and metastasis in gastric cancer by targeting Tgif2 PMID: 26464633
- Corneal fibroblasts demonstrate the expression of TGIF1 and TGIF2 transcription factors. These transcriptional repressors are critical, at least partially, in mediating the antifibrotic effect of vorinostat in the cornea. PMID: 26330748
- Shows that the homologous mouse Tgif2 gene is necessary for gastrulation. PMID: 20040491
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亞細胞定位：Nucleus. Note=Excluded from nucleoli.
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蛋白家族：TALE/TGIF homeobox family
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組織特異性：Widely expressed. Highly expressed in heart, kidney and testis. Weakly expressed in brain and prostate.
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數據庫鏈接：
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