TFEC Antibody

說明書

產品詳情

Uniprot No.：

O14948
基因名：

TFEC
別名：

bHLHe34 antibody; Class E basic helix-loop-helix protein 34 antibody; hTFEC-L antibody; TCFEC antibody; TFE-C antibody; Tfec antibody; TFEC protein antibody; TFEC_HUMAN antibody; TFECL antibody; Transcription factor EC antibody; Transcription factor EC-like antibody
宿主：

Rabbit
反應種屬：

Human,Mouse,Rat
免疫原：

Human TFEC
免疫原種屬：

Homo sapiens (Human)
抗體亞型：

IgG
純化方式：

Antigen Affinity Purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
產品提供形式：

Liquid
應用范圍：

ELISA,WB,IHC
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
Immunohistochemistry (IHC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Transcriptional regulator that acts as a repressor or an activator. Acts as a transcriptional repressor on minimal promoter containing element F (that includes an E-box sequence). Binds to element F in an E-box sequence-specific manner. Acts as a transcriptional transactivator on the proximal promoter region of the tartrate-resistant acid phosphatase (TRAP) E-box containing promoter. Collaborates with MITF in target gene activation. Acts as a transcriptional repressor on minimal promoter containing mu E3 enhancer sequence. Binds to mu E3 DNA sequence of the immunoglobulin heavy-chain gene enhancer. Binds DNA in a homo- or heterodimeric form.
基因功能參考文獻：
1. Two alternatively spliced TFEC isoforms have been found to be sequence-specific transcriptional activators of the nonmuscle myosin II heavy chain-A gene in transfected cells. PMID: 11467950
亞細胞定位：

Nucleus.
蛋白家族：

MiT/TFE family
組織特異性：

Expressed moderately in spleen, kidney, bone marrow, small intestine and leukocytes. Expressed weakly in testis, trachea and colon.
數據庫鏈接：

HGNC: 11754

OMIM: 604732

KEGG: hsa:22797

STRING: 9606.ENSP00000265440

UniGene: Hs.125962

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