TECPR1 Antibody, Biotin conjugated

說明書

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) TECPR1 Polyclonal antibody
Uniprot No.：

Q7Z6L1
基因名：

TECPR1
別名：

2210010N04Rik antibody; DKFZP434B0335 antibody; FLJ23419 antibody; FLJ90593 antibody; KIAA1358 antibody; MGC124730 antibody; mKIAA1358 antibody; RGD1306873 antibody; TCPR1_HUMAN antibody; Tecpr1 antibody; tectonin beta propeller repeat containing 1 antibody; Tectonin beta-propeller repeat-containing protein 1 antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Tectonin beta-propeller repeat-containing protein 1 protein (199-487AA)
免疫原種屬：

Homo sapiens (Human)
標記方式：

Biotin
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Tethering factor involved in autophagy. Involved in autophagosome maturation by promoting the autophagosome fusion with lysosomes: acts by associating with both the ATG5-ATG12 conjugate and phosphatidylinositol-3-phosphate (PtdIns(3)P) present at the surface of autophagosomes. Also involved in selective autophagy against bacterial pathogens, by being required for phagophore/preautophagosomal structure biogenesis and maturation.
基因功能參考文獻：
1. The concerted interactions among TECPR1, Atg12-Atg5, and PtdIns(3)P provide the fusion specificity between autophagosomes and lysosomes and that the assembly of this complex initiates the autophagosome maturation process. PMID: 22342342
亞細胞定位：

Cytoplasmic vesicle, autophagosome membrane. Lysosome membrane. Note=Localizes to Lysosome membranes, and binds PtdIns(3)P at the surface of autophagosome. Localizes to autolysosomes, a vesicle formed by the fusion between autophagosomes and lysosomes.
蛋白家族：

TECPR1 family
數據庫鏈接：

HGNC: 22214

OMIM: 614781

KEGG: hsa:25851

STRING: 9606.ENSP00000404923

UniGene: Hs.592281

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