TCEAL7 Antibody
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中文名稱：TCEAL7兔多克隆抗體
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貨號：CSB-PA863109LA01HU
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規(guī)格：￥440
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圖片：
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Western blot
All lanes: TCEAL7 antibody at 2µg/ml + A549 whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 13 kDa
Observed band size: 13 kDa -
Immunohistochemistry of paraffin-embedded human skeletal muscle tissue using CSB-PA863109LA01HU at dilution of 1:100 -
Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA863109LA01HU at dilution of 1:100
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其他：
產(chǎn)品詳情
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產(chǎn)品名稱：Rabbit anti-Homo sapiens (Human) TCEAL7 Polyclonal antibody
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Uniprot No.：
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基因名：TCEAL7
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別名：TCEAL7 antibody; Transcription elongation factor A protein-like 7 antibody; TCEA-like protein 7 antibody; Transcription elongation factor S-II protein-like 7 antibody
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宿主：Rabbit
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反應(yīng)種屬：Human
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免疫原：Recombinant Human Transcription elongation factor A protein-like 7 protein (1-100AA)
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免疫原種屬：Homo sapiens (Human)
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標(biāo)記方式：Non-conjugated
本頁面中的產(chǎn)品，TCEAL7 Antibody (CSB-PA863109LA01HU)，的標(biāo)記方式是Non-conjugated。對于TCEAL7 Antibody，我們還提供其他標(biāo)記。見下表：
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 -
產(chǎn)品提供形式：Liquid
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應(yīng)用范圍：ELISA, WB, IHC
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推薦稀釋比：
Application Recommended Dilution WB 1:500-1:2000 IHC 1:20-1:200 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評價
相關(guān)產(chǎn)品
靶點(diǎn)詳情
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功能：Plays a role in the negative regulation of NF-kappa-B signaling at the basal level by modulating transcriptional activity of NF-kappa-B on its target gene promoters. Associates with cyclin D1 promoter containing Myc E-box sequence and transcriptionally represses cyclin D1 expression. Regulates telomerase reverse transcriptase expression and telomerase activity in both ALT (alternative lengthening of telomeres)and telomerase-positive cell lines.
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基因功能參考文獻(xiàn)：
- Our study suggests that TCEAL7 might serve as a candidate tumor suppressor and a potential prognostic biomarker in gastric carcinogenesis. PMID: 23372750
- alteration of TCEAL7 expression levels in recombination-based alternative lengthening of telomeres and telomerase-positive cells affects hTERT expression PMID: 20454512
- TCEAL7 in the negative regulation of NF-kappaB signaling at the basal level by modulating transcriptional activity of NF-kappaB on its target gene promoters in ovarian cells. PMID: 19966855
- TCEAL7 is a cell death regulatory protein that is frequently inactivated in ovarian cancers, and may function as a tumor suppressor. PMID: 15870691
- A role for candidate tumor-suppressor gene TCEAL7 in the regulation of c-Myc activity, cyclin D1 levels and cellular transformation is reported. PMID: 18806825
- TCEAL7 polymorphisms may play a role in the development of invasive serous ovarian cancers. PMID: 19419758
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亞細(xì)胞定位：Nucleus.
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蛋白家族：TFS-II family, TFA subfamily
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組織特異性：Highly expressed in normal and fetal brain tissues, and weakly expressed in uterus and ovary. Down-regulated in epithelial ovarian, cervical, prostate, breast, brain and lung cancer cell lines and in brain and ovarian tumors.
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數(shù)據(jù)庫鏈接：
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