TACC2 Antibody
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中文名稱：TACC2兔多克隆抗體
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貨號：CSB-PA023066GA01HU
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規格：￥3,900
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其他：
產品詳情
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Uniprot No.：
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基因名：TACC2
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別名：TACC2 antibody; Transforming acidic coiled-coil-containing protein 2 antibody; Anti-Zuai-1 antibody; AZU-1 antibody
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宿主：Rabbit
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反應種屬：Human,Mouse,Rat
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免疫原：Human TACC2
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免疫原種屬：Homo sapiens (Human)
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抗體亞型：IgG
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純化方式：Antigen Affinity Purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
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產品提供形式：Liquid
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應用范圍：ELISA,WB,IHC
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Plays a role in the microtubule-dependent coupling of the nucleus and the centrosome. Involved in the processes that regulate centrosome-mediated interkinetic nuclear migration (INM) of neural progenitors. May play a role in organizing centrosomal microtubules. May act as a tumor suppressor protein. May represent a tumor progression marker.
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基因功能參考文獻：
- This finding suggests that TACC2 may be a useful tool as a candidate biomarker to predict the recurrence and prognosis of hepatocellular carcinoma. PMID: 29843208
- These results suggest that TACC2 plays an important role in the cell proliferation of breast carcinoma and therefore immunohistochemical TACC2 status is a candidate of worse prognostic factor in breast cancer cases. PMID: 27333920
- Differential expression of the transcripts TACC2 connects ubiquitin-proteasome system with infection-inflammation in preterm births and preterm premature rupture of membranes. PMID: 25884766
- Data suggest that TACC2 is highly expressed in prostate cancer cells and contributes to cell cycle progression and cell proliferation in androgen-nonresponsive prostate cancer cells; overexpression of TACC2 leads to recurrence of prostate cancer. PMID: 22456197
- Results revealed 3 genes highly predictive of event-free survival (EFS), beyond age and MLL status: FLT3, IRX2, and TACC2. PMID: 22210879
- TACC2 may mediate an oncogenic effect on breast cancer cells. PMID: 20335520
- Defects in TACC2 expression may affect gene regulation, thus contributing to the pathogenesis of some tumors. PMID: 12620397
- GCN5L2 is a TACC2-binding protein. PMID: 14767476
- Centrosomal TACC2 is required for mitotic spindle maintenance. PMID: 15304323
- Simian virus 40 large T antigen interacting with TACC2 is involved in stabilizing microtubules in mitosis. PMID: 19671663
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亞細胞定位：Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
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蛋白家族：TACC family
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組織特異性：Strongly expressed in heart, skeletal muscle, brain, prostate, thyroid and trachea.
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數據庫鏈接：
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