SUN5 Antibody

說明書

產品詳情

Uniprot No.：

Q8TC36
基因名：

SUN5
別名：

SUN5; SPAG4L; TSARG4; SUN domain-containing protein 5; Sad1 and UNC84 domain-containing protein 5; Sperm-associated antigen 4-like protein; Testis and spermatogenesis-related gene 4 protein
宿主：

Rabbit
反應種屬：

Human,Mouse,Rat
免疫原：

Human SPAG4L
免疫原種屬：

Homo sapiens (Human)
抗體亞型：

IgG
純化方式：

Antigen Affinity purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
產品提供形式：

Liquid
應用范圍：

ELISA,WB
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Plays an essential role in anchoring sperm head to the tail. Is responsible for the attachment of the coupling apparatus to the sperm nuclear envelope.
基因功能參考文獻：
1. The contribution of SUN5 mutations to acephalic spermatozoa might not be as high as described previously. PMID: 29331481
2. Results, together with those of the previous study, show that SUN5 is required for the formation of the sperm head-tail junction and male fertility. PMID: 28541472
3. results demonstrate that biallelic SUN5 mutations cause male infertility due to autosomal-recessive acephalic spermatozoa syndrome PMID: 27640305
4. SPAG4L may play an important role in the meiotic stage of spermatogenesis PMID: 21711156
相關疾?。?/div>
Spermatogenic failure 16 (SPGF16)
亞細胞定位：

Nucleus inner membrane; Single-pass membrane protein. Golgi apparatus.
組織特異性：

Sperm (at protein level). Widely expressed. Conflictingly shown to be specifically expressed in testis.
數據庫鏈接：

HGNC: 16252

OMIM: 613942

KEGG: hsa:140732

STRING: 9606.ENSP00000348496

UniGene: Hs.375186

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