SULT1C2 Antibody

說明書

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) SULT1C2 Polyclonal antibody
Uniprot No.：

O00338
基因名：

SULT1C2
別名：

humSULTC2 antibody; ST1C1 antibody; ST1C2 antibody; ST1C2_HUMAN antibody; Sulfotransferase 1C1 antibody; Sulfotransferase 1C2 antibody; Sulfotransferase family cytosolic 1C member 1 antibody; Sulfotransferase family cytosolic 1C member 2 antibody; SULT1C#1 antibody; SULT1C1 antibody; SULT1C2 antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Sulfotransferase 1C2 protein (1-120AA)
免疫原種屬：

Homo sapiens (Human)
標記方式：

Non-conjugated
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

Antigen Affinity Purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
產品提供形式：

Liquid
應用范圍：

ELISA, WB

推薦稀釋比：

Application	Recommended Dilution
WB	1:200-1:1000

Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation. Sulfonates p-nitrophenol, a small phenolic compond. Does not sulfonate steroids, dopamine, acetaminophen, or alpha-naphthol. Catalyzes the sulfonation of the carcinogenic N-Hydroxy-2-acetylaminofluorene leading to highly reactive intermediates capable of forming DNA adducts, potentially resulting in mutagenesis.
基因功能參考文獻：
1. Vitamin D receptor can interact directly with the SULT1C2 VDRE sequence to transcriptionally regulation SULT1C2 expression in colorectal tumor cells. PMID: 27130351
2. Our findings are the first to characterize the regulation of human SULT1C2 and SULT1C3 expression by several transcription factor activators. PMID: 24335393
3. gene resequencing and functional genomic studies PMID: 11740338
4. crystal structures of two members of SULT1 family, SULT1B1 and SULT1C1, both in complex with the product of the PAPS cofactor, adenosine-3-5-diphosphate (PAP). PMID: 16804942
亞細胞定位：

Cytoplasm. Lysosome.
蛋白家族：

Sulfotransferase 1 family
組織特異性：

Found in adult stomach, kidney and thyroid gland, and in fetal kidney and liver.
數據庫鏈接：

HGNC: 11456

OMIM: 602385

KEGG: hsa:6819

UniGene: Hs.436123

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