STX5 Antibody
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中文名稱：STX5兔多克隆抗體
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貨號：CSB-PA619754ESR1HU
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規格：￥440
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圖片：
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Immunohistochemistry of paraffin-embedded human lung tissue using CSB-PA619754ESR1HU at dilution of 1:100
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) STX5 Polyclonal antibody
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Uniprot No.：
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基因名：STX5
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別名：OTTHUMP00000185028 antibody; SED5 antibody; STX5 antibody; STX5_HUMAN antibody; STX5A antibody; Syntaxin 5 antibody; Syntaxin 5A antibody; Syntaxin-5 antibody; Syntaxin5 antibody; Syntaxin5A antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Recombinant Human Syntaxin-5 protein (55-355AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：Antigen Affinity Purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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產品提供形式：Liquid
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應用范圍：ELISA, IHC
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推薦稀釋比：
Application Recommended Dilution IHC 1:20-1:200 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Mediates endoplasmic reticulum to Golgi transport. Together with p115/USO1 and GM130/GOLGA2, involved in vesicle tethering and fusion at the cis-Golgi membrane to maintain the stacked and inter-connected structure of the Golgi apparatus.
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基因功能參考文獻：
- Expression of the Syn5 K270R mutant in cells impairs post-mitotic Golgi reassembly PMID: 27404360
- Together, these data strongly suggest that syntaxin 5-mediated retrograde transport to the Golgi apparatus is a broadly conserved feature of adeno-associated virus trafficking. PMID: 25410859
- Stx5 might play a role in modulating VLDL-R physiology by participating in an abrasively described or completely novel Golgi-bypass pathway. PMID: 23701949
- serum anti-STX5 autoantibody, which was discovered by a proteomic approach, is a potential new serum marker for the diagnosis of endometriosis. PMID: 21715015
- Depletion of syntaxin-5 complex components results in the accumulation of autophagosomes as a result of lysosomal dysfunction, leading to decreased degradation of autophagic substrates. PMID: 21242315
- Syx5 is required for the maintenance of the Golgi structures but may not play a major role in the transport of vesicles carrying proteins between the ER and the Golgi compartment. PMID: 16081076
- hypothesize that syntaxin 5 also has trafficking-independent functions PMID: 17389686
- depletion of GM130 by RNA interference slows the rate of ER to Golgi trafficking in vivo; interactions of GM130 with syntaxin 5 and Rab1 are regulated by mitotic phosphorylation PMID: 18167358
- Study shows that the SM protein, Sly1, interacts directly with the conserved oligomeric Golgi (COG) tethering complex; Sly1-COG interaction is mediated by the Cog4 subunit, which also interacts with Syntaxin 5 through a different binding site. PMID: 19536132
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亞細胞定位：Endoplasmic reticulum-Golgi intermediate compartment membrane; Single-pass type IV membrane protein. Golgi apparatus membrane.
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蛋白家族：Syntaxin family
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數據庫鏈接：
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