STK17B Antibody, FITC conjugated

說明書

中文名稱：

STK17B兔多克隆抗體, FITC偶聯(lián)
貨號(hào)：

CSB-PA022838LC01HU
規(guī)格：

￥880
其他：

產(chǎn)品詳情
產(chǎn)品評(píng)價(jià)
相關(guān)產(chǎn)品
靶點(diǎn)詳情

產(chǎn)品詳情

產(chǎn)品名稱：

Rabbit anti-Homo sapiens (Human) STK17B Polyclonal antibody
Uniprot No.：

O94768
基因名：

STK17B
別名：

DAP kinase related apoptosis inducing protein antibody; DAP kinase related apoptosis inducing protein kinase 2 antibody; DAP kinase-related apoptosis-inducing protein kinase 2 antibody; Death associated protein kinase related 2 antibody; DRAK 2 antibody; DRAK2 antibody; Serine/threonine kinase 17b antibody; Serine/threonine kinase 17b apoptosis inducing antibody; Serine/threonine protein kinase 17B antibody; Serine/threonine-protein kinase 17B antibody; ST17B_HUMAN antibody; STK 17B antibody; Stk17b antibody
宿主：

Rabbit
反應(yīng)種屬：

Human
免疫原：

Recombinant Human Serine/threonine-protein kinase 17B protein (235-366AA)
免疫原種屬：

Homo sapiens (Human)
標(biāo)記方式：

FITC
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產(chǎn)品提供形式：

Liquid
儲(chǔ)存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

功能：

Phosphorylates myosin light chains. Acts as a positive regulator of apoptosis.
基因功能參考文獻(xiàn)：
1. ChIP assays showed that in U937 cells MYB binds to a conserved element upstream of the DRAK2 transcription start site. PMID: 23398943
2. DRAK2 protein directly binds to the type I TGF-beta receptor and Knockdown of DRAK2 suppresses the tumorigenic ability of breast cancer cells. PMID: 23122956
3. DRAK2 and protein kinase D form a novel signaling module that controls calcium homeostasis following T cell activation. PMID: 21148796
4. DRAK2 kinase activity is regulated in a calcium-dependent manner and that Ser(12) phosphorylation is necessary for optimal suppression of T cell activation by this kinase PMID: 17182616
5. Strong suppression of T cell receptor signals during thymic selection caused by ectopic DRAK2 expression in a DRAK2 transgenic mouse model of autoimmune encephalomyelitis alters the responsiveness of peripheral T cells. PMID: 19542440
6. Regulation of the apoptosis-inducing kinase DRAK2 by cyclooxygenase-2 in colorectal cancer. PMID: 19638987
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亞細(xì)胞定位：

Nucleus. Cell membrane. Endoplasmic reticulum-Golgi intermediate compartment.
蛋白家族：

Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase subfamily
組織特異性：

Highly expressed in placenta, lung, pancreas. Lower levels in heart, brain, liver, skeletal muscle and kidney.
數(shù)據(jù)庫(kù)鏈接：

HGNC: 11396

OMIM: 604727

KEGG: hsa:9262

STRING: 9606.ENSP00000263955

UniGene: Hs.88297

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