ST3GAL3 Antibody, FITC conjugated

說(shuō)明書

中文名稱：

ST3GAL3兔多克隆抗體, FITC偶聯(lián)
貨號(hào)：

CSB-PA606136LC01HU
規(guī)格：

￥880
其他：

產(chǎn)品詳情
產(chǎn)品評(píng)價(jià)
相關(guān)產(chǎn)品
靶點(diǎn)詳情

產(chǎn)品詳情

產(chǎn)品名稱：

Rabbit anti-Homo sapiens (Human) ST3GAL3 Polyclonal antibody
Uniprot No.：

Q11203
基因名：

ST3GAL3
別名：

3 sialyltransferase antibody; 3(4) GlcNAc alpha-2 antibody; 3-sialyltransferase 3 antibody; 3-sialyltransferase antibody; 3-ST 3 antibody; 4-galactoside alpha-2 antibody; 4GlcNAc alpha 2 3 sialyltransferase antibody; Alpha 2 3 sialyltransferase II antibody; Alpha 2 3 sialyltransferase III antibody; Alpha 2 3 ST 3 antibody; Alpha 2 antibody; Beta galactoside alpha 3 sialyltransferase 3 antibody; Beta-galactoside alpha-2 antibody; CMP N acetylneuraminate beta 1 4 galactoside alpha 2 3 sialyltransferase antibody; CMP-N-acetylneuraminate-beta-1 antibody; EC 2.4.99.6 antibody; Gal beta 1 3 antibody; Gal beta 1 3(4) GlcNAc alpha 2 3 sialyltransferase antibody; Gal beta 1 3(4)GlcNAc alpha 2 3 sialyltransferase antibody; Gal beta-1 antibody; N acetyllactosaminide alpha 2 3 sialyltransferase antibody; N-acetyllactosaminide alpha-2 antibody; OTTHUMP00000008820 antibody; OTTHUMP00000008821 antibody; OTTHUMP00000008822 antibody; OTTHUMP00000008823 antibody; Sialyltransferase 6 (N acetyllacosaminide alpha 2 3 sialyltransferase) antibody; Sialyltransferase 6 antibody; SIAT6 antibody; SIAT6_HUMAN antibody; ST3 beta galactoside alpha 2 3 sialyltransferase 3 antibody; ST3 beta galactoside alpha 2,3 sialyltransferase 3 antibody; ST3Gal III antibody; St3gal3 antibody; ST3GALII antibody; ST3GalIII antibody; ST3N antibody
宿主：

Rabbit
反應(yīng)種屬：

Human
免疫原：

Recombinant Human CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase protein (29-375AA)
免疫原種屬：

Homo sapiens (Human)
標(biāo)記方式：

FITC
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產(chǎn)品提供形式：

Liquid
儲(chǔ)存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

功能：

Catalyzes the formation of the NeuAc-alpha-2,3-Gal-beta-1,4-GlcNAc-, NeuAc-alpha-2,3-Gal-beta-1,3-GlcNAc- and NeuAc-alpha-2,3-Gal-beta-1,3-GalNAc- sequences found in terminal carbohydrate groups of glycoproteins and glycolipids. The highest activity is toward Gal-beta-1,3-GlcNAc and the lowest toward Gal-beta-1,3-GalNAc.
基因功能參考文獻(xiàn)：
1. CA19.9 appears as a physiological product whose synthesis strongly depends on the tissue specific and epigenetically-regulated expression of B3GALT5 and ST3GAL3. PMID: 27535614
2. ST3Gal3 knockdown synergistically enhanced cisplatin-induced apoptosis in ovarian cancer cells PMID: 27871859
3. ST3Gal III modulates breast cancer cell adhesion and invasion by altering the expression of invasion-related molecules. PMID: 27779707
4. Dysfunctional ST3GAL3 may result in perturbation of the posttranslational sialylation of proteins in these pathways PMID: 23252400
5. ST3GAL3 mutations impair the development of higher cognitive functions. PMID: 21907012
6. Characterization of the promoter region of the ST3Gal III gene. PMID: 12697334
7. 19 different transcripts of ST3GalIII were isolated and cloned; tissue distribution analysis showed complex patterns in neural and muscular tissues PMID: 12815231
8. High levels of ST3GAL-III in the tumor tissue correlated with secondary local tumor recurrence (p = 0.005; p = 0.012). PMID: 12931020
9. Identification of a new ST3Gal3 transcript from fetal brain. PMID: 15316282
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相關(guān)疾病：

Mental retardation, autosomal recessive 12 (MRT12); Epileptic encephalopathy, early infantile, 15 (EIEE15)
亞細(xì)胞定位：

Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Secreted. Note=Membrane-bound form in trans cisternae of Golgi. Secreted into the body fluid.
蛋白家族：

Glycosyltransferase 29 family
組織特異性：

Highly expressed in adult skeletal muscle and in all fetal tissues examined and to a much lesser extent in placenta, lung and liver.
數(shù)據(jù)庫(kù)鏈接：

HGNC: 10866

OMIM: 606494

KEGG: hsa:6487

UniGene: Hs.597915

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