SRP14 Antibody, Biotin conjugated

說明書

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) SRP14 Polyclonal antibody
Uniprot No.：

P37108
基因名：

SRP14
別名：

18 kDa Alu RNA binding protein antibody; 18 kDa Alu RNA-binding protein antibody; Alu RNA-binding protein, 14-KD subunit antibody; ALURBP antibody; MGC14326 antibody; Signal recognition particle 14 kDa protein antibody; signal recognition particle 14kDa (homologous Alu RNA binding protein) antibody; SRP 14 antibody; SRP14 antibody; SRP14_HUMAN antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Signal recognition particle 14 kDa protein (2-107AA)
免疫原種屬：

Homo sapiens (Human)
標記方式：

Biotin
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding.
基因功能參考文獻：
1. SRP14 mutant proteins with absence of a peptide elongation delay caused inefficient targeting of preproteins leading to defects in secretion, depletion of proteins in the endogenous membranes, and reduced cell growth. PMID: 18455985
亞細胞定位：

Cytoplasm.
蛋白家族：

SRP14 family
數據庫鏈接：

HGNC: 11299

OMIM: 600708

KEGG: hsa:6727

STRING: 9606.ENSP00000267884

UniGene: Hs.533732

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