SPOPL Antibody, HRP conjugated
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中文名稱：
SPOPL兔多克隆抗體, HRP偶聯
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貨號：
CSB-PA022602LB01HU
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規格：
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其他：
產品詳情
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產品名稱：
Rabbit anti-Homo sapiens (Human) SPOPL Polyclonal antibody
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Uniprot No.：
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基因名：
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別名：
SPOPL antibody; Speckle-type POZ protein-like antibody; HIB homolog 2 antibody; Roadkill homolog 2 antibody
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宿主：
Rabbit
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反應種屬：
Human
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免疫原：
Recombinant Human Speckle-type POZ protein-like protein (1-120AA)
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免疫原種屬：
Homo sapiens (Human)
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標記方式：
HRP
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克隆類型：
Polyclonal
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抗體亞型：
IgG
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純化方式：
>95%, Protein G purified
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濃度：
It differs from different batches. Please contact us to confirm it.
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保存緩沖液：
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
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產品提供形式：
Liquid
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應用范圍：
ELISA
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Protocols：
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儲存條件：
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：
For Research Use Only. Not for use in diagnostic or therapeutic procedures.
靶點詳情
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功能：
Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins, but with relatively low efficiency. Cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complexes containing homodimeric SPOPL or the heterodimer formed by SPOP and SPOPL are less efficient than ubiquitin ligase complexes containing only SPOP. May function to down-regulate the activity of cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complexes that contain SPOP.
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基因功能參考文獻：
- Together, the data indicate that a CUL3-SPOPL E3 ubiquitin ligase complex regulates endocytic trafficking and formation of multivesicular bodies by ubiquitinating and degrading EPS15 at endosomes. PMID: 27008177
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亞細胞定位：
Nucleus.
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蛋白家族：
Tdpoz family
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數據庫鏈接：
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