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中文名稱：
SPAG1兔多克隆抗體
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貨號：
CSB-PA090256
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規格：
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圖片：
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The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using CSB-PA090256(SPAG1 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: ×200)
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The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using CSB-PA090256(SPAG1 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: ×200)
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Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Human colon tissue, Primary antibody: CSB-PA090256(SPAG1 Antibody) at dilution 1/600, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes
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其他：
產品詳情
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Uniprot No.：
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基因名：
SPAG1
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別名：
SPAG1 antibody; Sperm-associated antigen 1 antibody; HSD-3.8 antibody; Infertility-related sperm protein Spag-1 antibody
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宿主：
Rabbit
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反應種屬：
Human
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免疫原：
Synthetic peptide of Human SPAG1
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免疫原種屬：
Homo sapiens (Human)
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標記方式：
Non-conjugated
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抗體亞型：
IgG
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純化方式：
Antigen affinity purification
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濃度：
It differs from different batches. Please contact us to confirm it.
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保存緩沖液：
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
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產品提供形式：
Liquid
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應用范圍：
ELISA,WB,IHC
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推薦稀釋比：
| Application |
Recommended Dilution |
| ELISA |
1:1000-1:5000 |
| WB |
1:500-1:2000 |
| IHC |
1:25-1:100 |
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Protocols：
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儲存條件：
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：
For Research Use Only. Not for use in diagnostic or therapeutic procedures.
靶點詳情
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功能：
May play a role in the cytoplasmic assembly of the ciliary dynein arms. May play a role in fertilization. Binds GTP and has GTPase activity.
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基因功能參考文獻：
- SPAG1 probably plays a role in the cytoplasmic assembly. PMID: 24055112
- The h-Sp-1 molecule is expressed in sperm and testes and plays a role in fertilization. PMID: 12846798
- HSD-3.8 (SPAG1), interacts with G-protein beta 1 subunit and activates extracellular signal-regulated kinases 1 and 2 PMID: 16368546
- Immunocytochemical analysis demonstrated colocalization of SPAG1 with microtubules, and their association was confirmed by co-immunoprecipitation; subsequent motility assays further substantiated a potential role of SPAG1 in cancer cell motility PMID: 16983343
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相關疾病：
Ciliary dyskinesia, primary, 28 (CILD28)
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亞細胞定位：
Cytoplasm. Dynein axonemal particle. Note=Colocalizes with tubulin.
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組織特異性：
Present in most tissues, including lung, with the strongest expression in brain, colon, kidney, and testis. In sperm and testis, detected in particular in pachytene primary spermatocytes. Up-regulated in pancreatic tumor tissues and not in normal pancreat
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數據庫鏈接：
Most popular with customers
The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using CSB-PA090256(SPAG1 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: ×200)
The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using CSB-PA090256(SPAG1 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: ×200)
Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Human colon tissue, Primary antibody: CSB-PA090256(SPAG1 Antibody) at dilution 1/600, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes
