SNRK Antibody
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中文名稱：SNRK兔多克隆抗體
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貨號：CSB-PA868301NA01HU
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規格：￥440
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圖片：
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Western Blot
Positive WB detected in: 293T whole cell lysate, K562 whole cell lysate
All lanes: SNRK antibody at 1:2000
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 85, 28 kDa
Observed band size: 85 kDa
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) SNRK Polyclonal antibody
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Uniprot No.：
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基因名：SNRK
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別名：DKFZp779A1866 antibody; FLJ20224 antibody; HSNFRK antibody; KIAA0096 antibody; SNF related kinase antibody; SNF related serine/threonine protein kinase antibody; SNF-related serine/threonine-protein kinase antibody; SNF1 related kinase antibody; SNF1-related kinase antibody; SNFRK antibody; Snrk antibody; SNRK_HUMAN antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Peptide sequence from Human SNF-related serine/threonine-protein kinase protein (340-360AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
本頁面中的產品，SNRK Antibody (CSB-PA868301NA01HU)，的標記方式是Non-conjugated。對于SNRK Antibody，我們還提供其他標記。見下表：
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 -
產品提供形式：Liquid
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應用范圍：ELISA, WB
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推薦稀釋比：
Application Recommended Dilution WB 1:1000-1:5000 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：May play a role in hematopoietic cell proliferation or differentiation. Potential mediator of neuronal apoptosis.
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基因功能參考文獻：
- Study shows that TRIB3 binds to SNRK, and downregulates UCP3 through PPARalpha. SNRK is increased in cardiomyopathy patients, and SNRK reduces infarct size after ischaemia/reperfusion. SNRK also decreases cardiac cell death in a UCP3-dependent manner. PMID: 28117339
- Report the crystal structure of an N-terminal SNRK fragment containing kinase and adjacent ubiquitin-associated (UBA) domains. This structure shows that the UBA domain binds between the N- and C-lobes of the kinase domain. The mode of UBA binding in SNRK largely resembles that in AMPK and brain specific kinase (BRSK), however, unique interactions play vital roles in stabilizing the KD-UBA interface of SNRK. PMID: 29061304
- SNRK in cardiomyocytes is responsible for maintaining cardiac metabolic homeostasis, which is mediated in part by ROCK, and alteration of this homeostasis influences cardiac function in the adult heart. PMID: 27780848
- Differential expression of SNRK in early versus late stage disease suggests specific roles for SNRK in ovarian cancer metastasis. PMID: 28722495
- SNRK inhibits colon cancer cell proliferation through calcyclin-binding protein up-regulation and beta-catenin degradation, which results in reduced proliferation signaling. PMID: 22874833
- These findings reveal a novel function for SNRK in the regulation of colon cancer cell proliferation and beta-catenin signaling. PMID: 22874833
- SNRK could mediate some of the physiological effects of LKB1 PMID: 15733851
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亞細胞定位：Nucleus.
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蛋白家族：Protein kinase superfamily, CAMK Ser/Thr protein kinase family
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組織特異性：Expressed in hematopoietic progenitor cells and leukemic cell lines. Weakly expressed in the testis.
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數據庫鏈接：
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