SMAP1 Antibody

中文名稱：

SMAP1兔多克隆抗體
貨號：

CSB-PA811625LA01HU
規格：

￥440
圖片：
Immunohistochemistry of paraffin-embedded human appendix tissue using CSB-PA811625LA01HU at dilution of 1:100

Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA811625LA01HU at dilution of 1:100
其他：

產品詳情

標記方式：

Non-conjugated

本頁面中的產品，SMAP1 Antibody (CSB-PA811625LA01HU)，的標記方式是Non-conjugated。對于SMAP1 Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA811625LB01HU	SMAP1 Antibody, HRP conjugated	ELISA
FITC	CSB-PA811625LC01HU	SMAP1 Antibody, FITC conjugated
Biotin	CSB-PA811625LD01HU	SMAP1 Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA, IHC

推薦稀釋比：

Application	Recommended Dilution
IHC	1:20-1:200

Protocols：

ELISA Protocol
Immunohistochemistry (IHC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

GTPase activating protein that acts on ARF6. Plays a role in clathrin-dependent endocytosis. May play a role in erythropoiesis.
基因功能參考文獻：
1. The study identified a region on chromosome 6 comprising the genes SMAP1, B3GAT2, and RIMS1 as novel susceptibility locus for pediatric venous thromboembolism. PMID: 28011674
2. Results also demonstrated a physical association between SMAP1 and SMAP2, which might serve as a basis for a functional interaction, and identified the intramolecular domains responsible for this association PMID: 25281535
3. SMAP1 loss-of-function mutations in microsatellite instability colorectal cancer may contribute to the emerging oncogenic pathway involving abnormal Arf6 regulation. PMID: 23752192
4. SMAP1 may be an ADP-ribosylation factor 6 (Arf6)GAP that specifically regulates one of the multiple functions of Arf6, namely, clathrin-dependent endocytosis PMID: 15659652
亞細胞定位：

Cell membrane; Peripheral membrane protein; Cytoplasmic side.
組織特異性：

Detected in bone marrow, adrenal gland, trachea, lymph node, spinal cord, peripheral blood leukocytes, thyroid and stomach.
數據庫鏈接：

HGNC: 19651

OMIM: 611372

KEGG: hsa:60682

STRING: 9606.ENSP00000359484

UniGene: Hs.485717

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