SLK Antibody
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中文名稱：SLK兔多克隆抗體
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貨號：CSB-PA923093
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規(guī)格：￥2024
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圖片：
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Western blot analysis of extract from MCF-7 cells using SLK1 Antibody
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其他：
產(chǎn)品詳情
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產(chǎn)品名稱：Rabbit anti-Homo sapiens (Human) SLK Polyclonal antibody
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Uniprot No.：
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基因名：SLK
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宿主：Rabbit
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反應(yīng)種屬：Human
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免疫原：Peptide sequence around aa.1187~1191(K-T-L-E-E) derived from Human SLK1.
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免疫原種屬：Homo sapiens (Human)
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克隆類型：Polyclonal
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純化方式：Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
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濃度：It differs from different batches. Please contact us to confirm it.
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產(chǎn)品提供形式：Liquid
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應(yīng)用范圍：ELISA,WB
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推薦稀釋比：
Application Recommended Dilution WB 1:500-1:1000 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評價(jià)
相關(guān)產(chǎn)品
靶點(diǎn)詳情
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功能：Mediates apoptosis and actin stress fiber dissolution.
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基因功能參考文獻(xiàn)：
- SLK interacts with Tpr and alpha-actinin-4 in cells, and these protein-protein interactions may control the subcellular localization and the biological activity of SLK. PMID: 26094769
- SLK activated ERMs, together with Galphai, are critical for the correct localization of LGN-NuMA force generator complexes and hence for proper spindle orientation. PMID: 24958772
- The fact that SLK (LOSK) phosphorylates only a minor isoform 1A of p150(Glued) suggests that transport and microtubule-organizing functions of dynactin are distinctly divided between the two isoforms PMID: 23985322
- v-Src-dependent down-regulation of the Ste20-like kinase SLK through casein kinase II. PMID: 16837460
- we show that a novel isoform of SPS1-related proline alanine-rich kinase (SPAK/STE20) is involved in this inflammatory signaling cascade PMID: 17321610
- Protein kinase LOSK is required for radial microtubule organization and for the proper localization of Golgi complex in various cell types. PMID: 18287541
- Studies define an interaction between Neu and SLK signaling in the regulation of cancer cell motility. PMID: 19525980
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亞細(xì)胞定位：Cytoplasm.
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蛋白家族：Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily
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組織特異性：Ubiquitously expressed. Highest expression is found in heart and in skeletal muscle.
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數(shù)據(jù)庫鏈接：
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