SLCO3A1 Antibody, FITC conjugated
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中文名稱：SLCO3A1兔多克隆抗體, FITC偶聯
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貨號：CSB-PA883432LC01HU
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規格：￥880
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) SLCO3A1 Polyclonal antibody
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Uniprot No.：
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基因名：SLCO3A1
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別名：SLCO3A1 antibody; OATP3A1 antibody; OATPD antibody; SLC21A11 antibody; Solute carrier organic anion transporter family member 3A1 antibody; OATP3A1 antibody; Organic anion transporter polypeptide-related protein 3 antibody; OATP-RP3 antibody; OATPRP3 antibody; Organic anion-transporting polypeptide D antibody; OATP-D antibody; PGE1 transporter antibody; Sodium-independent organic anion transporter D antibody; Solute carrier family 21 member 11 antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Recombinant Human Solute carrier organic anion transporter family member 3A1 protein (439-539AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：FITC
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 -
產品提供形式：Liquid
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
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靶點詳情
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功能：Mediates the Na(+)-independent transport of organic anions such as estrone-3-sulfate. Mediates transport of prostaglandins (PG) E1 and E2, thyroxine (T4), deltorphin II, BQ-123 and vasopressin, but not DPDPE (a derivative of enkephalin lacking an N-terminal tyrosine residue), estrone-3-sulfate, taurocholate, digoxin nor DHEAS.
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基因功能參考文獻：
- OATP3A1 functions as a bile acid efflux transporter that is up-regulated as an adaptive response to cholestasis. PMID: 30063921
- SLCO3A1, a novel Crohn's disease-associated gene, mediates inflammatory processes in intestinal epithelial cells through NF-kappaB transcription activation. PMID: 24945726
- Single nucleotide polymorhpisms of SLCO3A1 were associated with nicotine dependence. PMID: 22377092
- OATP-D plays an important role in translocating prostaglandins in specialized tissues and cells. PMID: 14631946
- Further evidence is provided for the involvement of OATPs in oligopeptide transport. OATP3A1 variants might be involved in the regulation of extracellular vasopressin concentration in human brain. PMID: 16971491
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亞細胞定位：Cell membrane; Multi-pass membrane protein.
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蛋白家族：Organo anion transporter (TC 2.A.60) family
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組織特異性：Ubiquitous. Highly expressed in spleen and leukocytes. Generally the expression of isoform 1 is higher than that of isoform 2. Isoform 2 is particularly abundant in testis and brain. In testis, isoform 1 is detected in spermatogonia at different stages an
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