SLC4A8 Antibody, HRP conjugated

說明書

產(chǎn)品詳情

產(chǎn)品名稱：

Rabbit anti-Homo sapiens (Human) SLC4A8 Polyclonal antibody
Uniprot No.：

Q2Y0W8
基因名：

SLC4A8
別名：

Electroneutral Na(+)-driven Cl-HCO3 exchanger antibody; Electroneutral sodium bicarbonate exchanger 1 antibody; k-NBC3 antibody; S4A8_HUMAN antibody; Slc4a8 antibody; SLC4A8 protein antibody; Solute carrier family 4 member 8 antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Electroneutral sodium bicarbonate exchanger 1 protein (1-300AA)
免疫原種屬：

Homo sapiens (Human)
標記方式：

HRP
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

Antigen Affinity Purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產(chǎn)品提供形式：

Liquid
應用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Mediates electroneutral sodium- and carbonate-dependent chloride-HCO3(-) exchange with a Na(+):HCO3(-) stoichiometry of 2:1. Plays a major role in pH regulation in neurons. May be involved in cell pH regulation by transporting HCO3(-) from blood to cell. Enhanced expression in severe acid stress could be important for cell survival by mediating the influx of HCO3(-) into the cells. Also mediates lithium-dependent HCO3(-) cotransport. May be regulated by osmolarity.
基因功能參考文獻：
1. This study confirmed the presence in human cDNA of mouse NDCBE-like transcripts (human NDCBE-A) and three novel transcripts NDCBE-C, NDCBE-D, and NDCBE-D'. PMID: 18577713
亞細胞定位：

Membrane; Multi-pass membrane protein.
蛋白家族：

Anion exchanger (TC 2.A.31) family
組織特異性：

Expressed in the pyramidal cells of the hippocampus (at protein level). Highly expressed in all major regions of the brain, spinal column and in testis, and moderate levels in trachea, thyroid and medulla region of kidney. Low expression levels observed i
數(shù)據(jù)庫鏈接：

HGNC: 11034

OMIM: 605024

KEGG: hsa:9498

STRING: 9606.ENSP00000405812

UniGene: Hs.4749

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