SLC35A2 Antibody, Biotin conjugated

說明書

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) SLC35A2 Polyclonal antibody
Uniprot No.：

P78381
基因名：

SLC35A2
別名：

SLC35A2 antibody; UGALT antibody; UGT antibody; UGTL antibody; UDP-galactose translocator antibody; Solute carrier family 35 member A2 antibody; UDP-galactose transporter antibody; UDP-Gal-Tr antibody; UGT antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human UDP-galactose translocator protein (136-234AA)
免疫原種屬：

Homo sapiens (Human)
標記方式：

Biotin
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Transports nucleotide sugars from the cytosol into Golgi vesicles where glycosyltransferases function.
基因功能參考文獻：
1. The short N-terminal region composed of 35 N-terminal amino-acid residues of UGT was crucial for galactosylation of N-glycans. PMID: 25451267
2. UDP-galactose (SLC35A2) and UDP-N-acetylglucosamine (SLC35A3) Transporters Form Glycosylation-related Complexes with Mannoside Acetylglucosaminyltransferases (Mgats). PMID: 25944901
3. De novo mutations in SLC35A2 encoding a UDP-galactose transporter cause early-onset epileptic encephalopathy. PMID: 24115232
4. The data further supports the hypothesis that UGT and NGT cooperate in the UDP-Gal delivery for glycosyltransferases located in the Golgi apparatus. PMID: 23583405
5. Mosaicism of the UDP-galactose transporter SLC35A2 causes a congenital disorder of glycosylation. PMID: 23561849
6. localization of the UDP-Gal transporter may depend on the presence of the partner splice variant PMID: 21918738
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相關疾病：

Congenital disorder of glycosylation 2M (CDG2M)
亞細胞定位：

Golgi apparatus membrane; Multi-pass membrane protein.
蛋白家族：

Nucleotide-sugar transporter family, SLC35A subfamily
數(shù)據(jù)庫鏈接：

HGNC: 11022

OMIM: 300896

KEGG: hsa:7355

STRING: 9606.ENSP00000247138

UniGene: Hs.21899

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