SLC25A10 Antibody

說明書

產品詳情

Uniprot No.：

Q9UBX3
基因名：

SLC25A10
別名：

SLC25A10; DIC; Mitochondrial dicarboxylate carrier; Solute carrier family 25 member 10
宿主：

Rabbit
反應種屬：

Human,Mouse,Rat
免疫原：

Human SLC25A10
免疫原種屬：

Homo sapiens (Human)
抗體亞型：

IgG
純化方式：

Antigen Affinity Purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
產品提供形式：

Liquid
應用范圍：

ELISA,WB
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Involved in translocation of malonate, malate and succinate in exchange for phosphate, sulfate, sulfite or thiosulfate across mitochondrial inner membrane.
基因功能參考文獻：
1. study identifies novel genes associated with insulin sensitivity in adipocytes in women independently of obesity. KFL15 and SLC25A10 are inhibitors of insulin-stimulated lipogenesis under conditions when glucose transport is the rate limiting step PMID: 28570579
2. the SLC25A10 carrier plays an important role in regulating redox homeostasis to protect confluent cells against oxidative stress. PMID: 25797253
3. Compares and contrasts all the known human SLC25A* genes and includes functional information. PMID: 23266187
4. SLC25A10 is a target gene of the BACH1 transcription factor according to ChIP-seq analysis in HEK 293 cells. PMID: 21555518
5. Slc25a10 plays an important role in supplying malate for citrate transport required for fatty acid synthesis and its inhibition might effectively reduce lipid accumulation in adipose tissues PMID: 16027120
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亞細胞定位：

Mitochondrion inner membrane; Multi-pass membrane protein.
蛋白家族：

Mitochondrial carrier (TC 2.A.29) family
組織特異性：

Present in high amounts in liver and kidney, and at lower levels in all the other tissues analyzed.
數據庫鏈接：

HGNC: 10980

OMIM: 606794

KEGG: hsa:1468

STRING: 9606.ENSP00000345580

UniGene: Hs.548187

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