SH2D4A Antibody
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中文名稱：SH2D4A兔多克隆抗體
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貨號：CSB-PA050002
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規格：￥1090
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其他：
產品詳情
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Uniprot No.：
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基因名：SH2D4A
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別名：FLJ20967 antibody; PPP1R38 antibody; Protein phosphatase 1 regulatory subunit 38 antibody; Protein SH antibody; Protein SH(2)A antibody; Protein SH2A antibody; SH2 domain containing 4A antibody; SH2 domain containing protein 4A antibody; SH2 domain-containing protein 4A antibody; SH24A_HUMAN antibody; SH2A antibody; Sh2d4a antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Synthesized peptide derived from the Internal region of Human SH2D4A.
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
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抗體亞型：IgG
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純化方式：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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產品提供形式：Liquid
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應用范圍：IHC, ELISA
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推薦稀釋比：
Application Recommended Dilution IHC 1:100-1:300 ELISA 1:20000 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Inhibits estrogen-induced cell proliferation by competing with PLCG for binding to ESR1, blocking the effect of estrogen on PLCG and repressing estrogen-induced proliferation. May play a role in T-cell development and function.
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基因功能參考文獻：
- The chromosome 8p tumor suppressor genes SORBS3 and SH2D4A are physically and functionally linked and provide a molecular mechanism of inhibiting STAT3-mediated IL-6 signaling in hepatocellular carcinoma cells. PMID: 27311882
- New evidence for SH2D4A involvement in hepatocellular carcinoma pathogenesis demonstrating for the first time its deregulation in cirrhotic nodules. PMID: 24315626
- SH2D4A is dispensable for TCR signal transduction in T cells PMID: 18641339
- SH2D4A inhibited cell proliferation by suppression of the ERalpha/PLC-gamma/PKC signaling pathway. PMID: 19712589
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亞細胞定位：Cytoplasm.
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組織特異性：Ubiquitously expressed. Aberrantly expressed in some cancers.
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數據庫鏈接：
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