SF3B6 Antibody, FITC conjugated
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中文名稱：SF3B6兔多克隆抗體, FITC偶聯
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貨號：CSB-PA897543LC01HU
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規格：￥880
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) SF3B6 Polyclonal antibody
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Uniprot No.：
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基因名：SF3B6
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別名：Ht006 antibody; P14 antibody; PM14_HUMAN antibody; Pre mRNA branch site protein p14 antibody; Pre-mRNA branch site protein p14 antibody; SAP14 antibody; SF3B 14 kDa subunit antibody; SF3B14 antibody; SF3B14a antibody; Splicing factor 3B, 14 kDa subunit antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Recombinant Human Splicing factor 3B subunit 6 protein (1-125AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：FITC
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 -
產品提供形式：Liquid
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
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靶點詳情
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功能：Involved in pre-mRNA splicing as a component of the splicing factor SF3B complex. SF3B complex is required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Directly contacts the pre-mRNA branch site adenosine for the first catalytic step of splicing. Enters the spliceosome and associates with the pre-mRNA branch site as part of the 17S U2 or, in the case of the minor spliceosome, as part of the 18S U11/U12 snRNP complex, and thus may facilitate the interaction of these snRNP with the branch sites of U2 and U12 respectively.
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基因功能參考文獻：
- the p14-RNA interaction screens charges on the backbone of the branch site during spliceosome assembly. PMID: 26784522
- determined the high resolution structure of a complex between SF3b14 and a peptide derived from SF3b155 and proposed a model for recognition of the pre-mRNA branch sequence adenosine. PMID: 16432215
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亞細胞定位：Nucleus.
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蛋白家族：SF3B6 family
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數據庫鏈接：
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