SENP5 Antibody
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中文名稱：SENP5兔多克隆抗體
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貨號：CSB-PA911693
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規格：￥2024
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圖片：
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Western blot analysis of extracts from COS7 cells, using SENP5 antibody. -
Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue using SENP5 antibody.
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) SENP5 Polyclonal antibody
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Uniprot No.：
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基因名：SENP5
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宿主：Rabbit
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反應種屬：Human,Mouse
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免疫原：Synthesized peptide derived from Internal of Human SENP5.
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免疫原種屬：Homo sapiens (Human)
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克隆類型：Polyclonal
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純化方式：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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濃度：It differs from different batches. Please contact us to confirm it.
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產品提供形式：Liquid
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應用范圍：ELISA,WB,IHC
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推薦稀釋比：
Application Recommended Dilution WB 1:500-1:3000 IHC 1:50-1:100 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO3 to its mature form and deconjugation of SUMO2 and SUMO3 from targeted proteins. Has weak proteolytic activity against full-length SUMO1 or SUMO1 conjugates. Required for cell division.
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基因功能參考文獻：
- Results from a study on gene expression variability markers in early-stage human embryos shows that SENP5 is a putative expression variability marker for the 3-day, 8-cell embryo stage. PMID: 26288249
- Mild oxidative stress stabilized the SENP5 protein in the oral squamous cell carcinoma cells, and only the combination of SENP5 silencing and H2O2 application led to mitochondria fragmentation and a significant increase in cell apoptosis. PMID: 25901414
- Low expression of SENP5 is associated with good prognosis among breast cancer patients. PMID: 24658161
- Knockdown of SENP5 resulted in increased levels of SUMO-1 and SUMO-2/3, inhibition of cell proliferation, defects in nuclear morphology, and appearance of binucleate cells, revealing an essential role for SENP5 in mitosis and/or cytokinesis. PMID: 16738315
- altered subcellular localization of SENP5 in oral squamous cell carcinoma (OSCC) cells and the correlation between SENP5 expression and the differentiation of OSCC. PMID: 18949399
- Nucleolar protein B23/nucleophosmin regulates the vertebrate SUMO pathway through SENP3 and SENP5 proteases. PMID: 19015314
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亞細胞定位：Nucleus, nucleolus.
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蛋白家族：Peptidase C48 family
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數據庫鏈接：
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