SEMA6B Antibody

中文名稱：

SEMA6B兔多克隆抗體
貨號：

CSB-PA862010LA01HU
規格：

￥440
圖片：
IHC image of CSB-PA862010LA01HU diluted at 1:100 and staining in paraffin-embedded human brain tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

Immunofluorescence staining of Hela cells with CSB-PA862010LA01HU at 1:33, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
其他：

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) SEMA6B Polyclonal antibody
Uniprot No.：

Q9H3T3
基因名：

SEMA6B
別名：

SEM-SEMA-Y antibody; SEM6B_HUMAN antibody; sema domain; transmembrane domain (TM); and cytoplasmic domain; (semaphorin) 6B antibody; Sema Z antibody; SEMA-VIB antibody; Sema6b antibody; SEMAN antibody; semaphorin VIB antibody; Semaphorin-6B antibody; semaphorin-6Ba antibody; Semaphorin-Z antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Semaphorin-6B protein (756-888AA)
免疫原種屬：

Homo sapiens (Human)

標記方式：

Non-conjugated

本頁面中的產品，SEMA6B Antibody (CSB-PA862010LA01HU)，的標記方式是Non-conjugated。對于SEMA6B Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA862010LB01HU	SEMA6B Antibody, HRP conjugated	ELISA
FITC	CSB-PA862010LC01HU	SEMA6B Antibody, FITC conjugated
Biotin	CSB-PA862010LD01HU	SEMA6B Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA, IHC, IF

推薦稀釋比：

Application	Recommended Dilution
IHC	1:20-1:200
IF	1:20-1:200

Protocols：

ELISA Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Functions as a cell surface repellent for mossy fibers of developping neurons in the hippocampus where it plays a role in axon guidance. May function through the PLXNA4 receptor expressed by mossy cell axons.; (Microbial infection) Acts as a receptor for P.sordellii toxin TcsL in the in the vascular endothelium.
基因功能參考文獻：
1. Semaphorin 6B is related to tumour differentiation and metastasis in vivo, and tumour cell migration, adhesion and invasion in vitro. PMID: 23781008
2. states a clear relation among breast cancer and SEMA6B expression; moreover we describe for the first time the SEMA6Ba protein and report here the analysis of SEMA6Ba RNA messenger, the protein expression and the cellular localization PMID: 23665584
3. Gene SEMA6B is strongly down regulated by peroxisome proliferator-activated receptors. PMID: 15177567
亞細胞定位：

Cell membrane; Single-pass type I membrane protein.
蛋白家族：

Semaphorin family
組織特異性：

Expressed in the brain in GABAergic neurons.
數據庫鏈接：

HGNC: 10739

OMIM: 608873

KEGG: hsa:10501

STRING: 9606.ENSP00000301293

UniGene: Hs.465642

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