SCARA3 Antibody

中文名稱：

SCARA3兔多克隆抗體
貨號：

CSB-PA721489LA01HU
規(guī)格：

￥440
圖片：
Immunohistochemistry of paraffin-embedded human small intestine tissue using CSB-PA721489LA01HU at dilution of 1:100
其他：

產品詳情
產品評價
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靶點詳情

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) SCARA3 Polyclonal antibody
Uniprot No.：

Q6AZY7
基因名：

SCARA3
別名：

APC7 antibody; Cellular stress response antibody; Cellular stress response gene protein antibody; CSR antibody; CSR1 antibody; Macrophage scavenger receptor-like 1 antibody; MSLR1 antibody; MSRL1 antibody; SCAR3_HUMAN antibody; SCARA3 antibody; Scavenger receptor class A member 3 antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Scavenger receptor class A member 3 protein (201-466AA)
免疫原種屬：

Homo sapiens (Human)

標記方式：

Non-conjugated

本頁面中的產品，SCARA3 Antibody (CSB-PA721489LA01HU)，的標記方式是Non-conjugated。對于SCARA3 Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA721489LB01HU	SCARA3 Antibody, HRP conjugated	ELISA
FITC	CSB-PA721489LC01HU	SCARA3 Antibody, FITC conjugated
Biotin	CSB-PA721489LD01HU	SCARA3 Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

Antigen Affinity Purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA, IHC

推薦稀釋比：

Application	Recommended Dilution
IHC	1:20-1:200

Protocols：

ELISA Protocol
Immunohistochemistry (IHC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

功能：

Seems to protect cells by scavenging oxidative molecules or harmful products of oxidation.
基因功能參考文獻：
1. CSR1 is SUMOylated at K582 and rapid ubiquitinated and degradated in prostate cancer cells. PMID: 29705808
2. demonstrated that CSR1 inhibited hepatocellular carcinoma cell proliferation, migration and invasion through inactivation of hematopoietic PBX interacting protein (HPIP) and its downstream PI3K/AKT signaling pathway. PMID: 28975986
3. Suppression of CSR1 expression is a novel mechanism critical for the oncogenic activity of miR-650. PMID: 25956032
4. Findings regarding the interaction of NADPH-P450 reductase (NPR) with cellular stress response (CSR) indicated function of NPR in hypoxic response. PMID: 24491563
5. Data indicate that the clinical samples showed an inverse correlation between SCARA3 gene expression, myeloma progression, and favorable clinical prognosis. PMID: 23537707
6. The binding of CSR1 with XIAP enhanced caspase-9 and caspase-3 protease activities. PMID: 22683311
7. The consistently high SCARA3 levels in both primary carcinomas and metastatic cells in effusions, and its up-regulation along disease progression from diagnosis to recurrence, suggest a role in ovarian cancer biology. PMID: 21855113
8. Results demonstrate the involvement of SCARA3 and SCARA5 in the uptake of PF14-oligonucleotide nanocomplexes. PMID: 22138034
9. Down-regulation of CSR1 protein expression by promoter methylation is associated with tumor growth and metastasis of prostate cancer PMID: 16436673
10. CSR1 appears to induce cell death through a novel mechanism by hijacking a critical RNA processing enzyme CPSF3. PMID: 18806823
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亞細胞定位：

Endoplasmic reticulum membrane; Single-pass type II membrane protein. Golgi apparatus membrane; Single-pass type II membrane protein. Note=Endoplasmic reticulum and/or Golgi.
組織特異性：

Expressed ubiquitously.
數據庫鏈接：

HGNC: 19000

OMIM: 602728

KEGG: hsa:51435

STRING: 9606.ENSP00000301904

UniGene: Hs.128856

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