SCAPER Antibody, Biotin conjugated

說明書

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) SCAPER Polyclonal antibody
Uniprot No.：

Q9BY12
基因名：

SCAPER
別名：

SCAPER antibody; KIAA1454 antibody; ZNF291 antibody; MSTP063 antibody; S phase cyclin A-associated protein in the endoplasmic reticulum antibody; S phase cyclin A-associated protein in the ER antibody; Zinc finger protein 291 antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human S phase cyclin A-associated protein in the endoplasmic reticulum protein (1109-1400AA)
免疫原種屬：

Homo sapiens (Human)
標記方式：

Biotin
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

CCNA2/CDK2 regulatory protein that transiently maintains CCNA2 in the cytoplasm.
基因功能參考文獻：
1. An unstable [CCTG](n) repeat in the second intron of the ZNF291 gene, on chromosome 15q21-24, was identified. PMID: 17553665
2. Study describes the biochemically purification and identification of SCAPER, a novel protein that specifically interacts with cyclin A/Cdk2 in vivo. PMID: 17698606
3. By sequestering cyclin A/Cdk2, SCAPER is capable of directing the activity of this kinase complex away from the nucleus and regulating cyclin A/Cdk2 equilibrium in distinct subcellular compartments. PMID: 18245951
亞細胞定位：

Endoplasmic reticulum. Nucleus. Note=Predominantly located in the endoplasmic reticulum, only a small portion is detected in the nucleus.
組織特異性：

Widely expressed with high expression in testis. Isoform 1 is detected in various tissues, including retina, fetal and adult brain. Isoform 2 is expressed in the retina at high levels, and in the brain at very low levels.
數據庫鏈接：

HGNC: 13081

OMIM: 611611

KEGG: hsa:49855

STRING: 9606.ENSP00000326924

UniGene: Hs.458986

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