RUFY1 Antibody

說明書

產品詳情

Uniprot No.：

Q96T51
基因名：

RUFY1
別名：

3000002E04Rik antibody; FLJ22251 antibody; FYVE finger protein EIP1 antibody; FYVE-finger protein EIP1 antibody; La binding protein 1 antibody; La-binding protein 1 antibody; OTTHUMP00000161521 antibody; Rab4 interacting protein antibody; Rab4-interacting protein antibody; RABIP4 antibody; RUFY1 antibody; RUFY1_HUMAN antibody; RUN and FYVE domain containing 1 antibody; RUN and FYVE domain-containing protein 1 antibody; RUN and FYVE domains containing protein 1 antibody; ZFYVE12 antibody; Zinc finger FYVE domain containing protein 12 antibody; Zinc finger FYVE domain-containing protein 12 antibody
宿主：

Rabbit
反應種屬：

Human,Mouse
免疫原：

Synthesized peptide derived from the Internal region of Human RUFY1.
免疫原種屬：

Homo sapiens (Human)
標記方式：

Non-conjugated
抗體亞型：

IgG
純化方式：

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
產品提供形式：

Liquid
應用范圍：

WB, ELISA

推薦稀釋比：

Application	Recommended Dilution
WB	1:500-1:2000
ELISA	1:10000

Protocols：

Western Blotting (WB) Protocol
ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates in early endosomal trafficking.
基因功能參考文獻：
1. RUFY1 may be involved in endolysosomal transport-a process known to be important to development of early onset AD. PMID: 28738127
2. Data indicate that RUN and FYVE domain protein Rabip4'(RUFY1) interacts specifically and directly with adaptor protein complex AP-3. PMID: 23144738
3. These findings suggest that Rab14 and Rab4 act sequentially, together with RUFY1. PMID: 20534812
4. interaction with tyrosine kinase Etk PMID: 11877430
亞細胞定位：

Cytoplasm. Early endosome membrane; Peripheral membrane protein.
組織特異性：

Broadly expressed, with highest levels in lung, testis, kidney and brain.
數(shù)據(jù)庫鏈接：

HGNC: 19760

OMIM: 610327

KEGG: hsa:80230

STRING: 9606.ENSP00000325594

UniGene: Hs.306769

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