RTRAF Antibody

說明書

中文名稱：

RTRAF兔多克隆抗體
貨號：

CSB-PA896684ESR1HU
規格：

￥440
圖片：
Western blot
All lanes: C14orf166 antibody at 6μg/ml + Mouse lung tissue
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 28 kDa
Observed band size: 28 kDa

Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA896684ESR1HU at dilution of 1:100

Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA896684ESR1HU at dilution of 1:100
其他：

產品詳情
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靶點詳情

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) RTRAF Polyclonal antibody
Uniprot No.：

Q9Y224
基因名：

RTRAF
別名：

C14orf166 antibody; CGI 99 antibody; CGI-99 antibody; CGI99 antibody; Chromosome 14 open reading frame 166 antibody; CLE antibody; CLE7 antibody; CN166_HUMAN antibody; Homeobox prox 1 antibody; LCRP369 antibody; RLL motif containing 1 antibody; RLLM1 antibody; UPF0568 protein C14orf166 antibody
宿主：

Rabbit
反應種屬：

Human, Mouse
免疫原：

Recombinant Human RNA transcription, translation and transport factor protein (1-244AA)
免疫原種屬：

Homo sapiens (Human)
標記方式：

Non-conjugated
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

Antigen Affinity Purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
產品提供形式：

Liquid
應用范圍：

ELISA, WB, IHC

推薦稀釋比：

Application	Recommended Dilution
WB	1:500-1:2000
IHC	1:20-1:200

Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
Immunohistochemistry (IHC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

功能：

RNA-binding protein involved in modulation of mRNA transcription by Polymerase II. Component of the tRNA-splicing ligase complex and is required for tRNA ligation. May be required for RNA transport.; (Microbial infection) In case of infection by influenza virus A (IVA), is involved in viral replication.
基因功能參考文獻：
1. C14ORF166 may represent a biomarker of pelvic lymph node metastasis in uterine cervical cancer PMID: 26219895
2. C14orf166, a cellular protein required for viral replication, is incorporated into influenza virus particles. PMID: 26864902
3. C14orf166 promotes bladder cancer cell proliferation and can be a novel prognostic biomarker for patients with bladder cancer. PMID: 26905879
4. C14orf166 could be a novel prognostic biomarker of breast cancer, it also contributes to cell proliferation by regulating G1/S transition. PMID: 26883017
5. Overexpression of chromosome 14 open reading frame 166 correlates with disease progression in nasopharyngeal carcinoma. PMID: 25964093
6. Silencing of CLE causes reduction of influenza A virus polymerase activity, viral RNA transcription and replication, virus titer, and viral particle production. PMID: 21900157
7. spatial interactions of hnRNPH1, NF45, and C14orf166 with HCVc174 likely modulate HCV or cellular functions during acute and chronic HCV infection PMID: 21823664
8. A novel protein CGI-99 is isolated, which may be involved in the functional regulation of human ninein in the centrosome structure and may also be important in brain development and tumorigenesis. PMID: 15147888
9. c14orf166 was identified asa novel metastasis-associated protein, and the roles of radixin, moesin and c14orf166 in pancreatic cancer metastasis deserve further investigations. PMID: 19152423
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亞細胞定位：

Nucleus. Cytoplasm, cytosol. Cytoplasm, perinuclear region. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.; Nucleus. Cytoplasm.
蛋白家族：

RTRAF family
組織特異性：

Widely expressed. Expressed at high level in heart and skeletal muscle. Expressed at intermediate level in liver, pancreas, fetal brain and fetal lung. Weakly expressed in adult brain, adult lung, placenta, fetal liver and fetal kidney. Overexpressed in m
數據庫鏈接：

HGNC: 23169

OMIM: 610858

KEGG: hsa:51637

STRING: 9606.ENSP00000261700

UniGene: Hs.534457

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