RPLP0 Antibody

中文名稱：

RPLP0兔多克隆抗體
貨號：

CSB-PA020336LA01HU
規格：

￥440
圖片：
Western Blot
Positive WB detected in: Rat brain tissue, Rat kidney tissue, Mouse kidney tissue
All lanes: RPLP0 antibody at 3.4µg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 35, 28 kDa
Observed band size: 35 kDa

Immunocytochemistry analysis of human pancreatic tissue using CSB-PA020336LA01HU at dilution of 1:100

Immunocytochemistry analysis of human glioma using CSB-PA020336LA01HU at dilution of 1:100

Immunofluorescent analysis of Hela cells using CSB-PA020336LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
其他：

產品詳情
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靶點詳情

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) RPLP0 Polyclonal antibody
Uniprot No.：

P05388
基因名：

RPLP0
別名：

36B4 antibody; 60S acidic ribosomal protein P0 antibody; 60S ribosomal protein L10E antibody; Acidic ribosomal phosphoprotein P0 antibody; Arbp antibody; L10E antibody; LP0 antibody; MGC107165 antibody; MGC107166 antibody; MGC111226 antibody; MGC88175 antibody; OTTMUSP00000015585 antibody; P0 antibody; PRLP0 antibody; Ribosomal phosphoprotein; acidic; P0 antibody; Ribosomal protein P0 antibody; Ribosomal protein; large; P0 antibody; RLA0_HUMAN antibody; rplP0 antibody; RPP0 antibody
宿主：

Rabbit
反應種屬：

Human, Mouse, Rat
免疫原：

Recombinant Human 60S acidic ribosomal protein P0 protein (1-317AA)
免疫原種屬：

Homo sapiens (Human)

標記方式：

Non-conjugated

本頁面中的產品，RPLP0 Antibody (CSB-PA020336LA01HU)，的標記方式是Non-conjugated。對于RPLP0 Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA020336LB01HU	RPLP0 Antibody, HRP conjugated	ELISA
FITC	CSB-PA020336LC01HU	RPLP0 Antibody, FITC conjugated
Biotin	CSB-PA020336LD01HU	RPLP0 Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA, WB, IHC, IF

推薦稀釋比：

Application	Recommended Dilution
WB	1:500-1:5000
IHC	1:20-1:200
IF	1:50-1:200

Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

功能：

Ribosomal protein P0 is the functional equivalent of E.coli protein L10.
基因功能參考文獻：
1. The presence of uL10 on the ribosomes is affected in stressed cells, thus it might be considered as a regulatory element responding to environmental fluctuations. PMID: 28986221
2. absence of RPLP0, RPLP1, or RPLP2 resulted in reactive oxygen species (ROS) accumulation and MAPK1/ERK2 signaling pathway activation. PMID: 26176264
3. This study shows a spontaneous humoral immune response to ribosomal P0 protein in colorectal cancer patients. PMID: 25889931
4. Down-regulation of RPLP0 resulted in G1 arrest of gastric cancer cells PMID: 25433997
5. the immune response mediated by serum anti-RPLP0 and anti-galectin 3 antibodies plays a key role in the pathogenesis of SLE skin lesions. These findings provide new insights into the mechanism of SLE-related organ disorders. PMID: 25307291
6. Evaluated autoantibodies against native ribosomal P complex and recombinant ribosomal P proteins (anti-Rib-P0, anti-Rib-P1, anti-Rib-P2) for prevalence, diagnostic relevance&clinical associations in a Chinese cohort with systemic lupus erythematosus. PMID: 23400861
7. P proteins are up-regulated in a considerable number of patients with the most common types of cancer. PMID: 21040949
8. The P0 protein was found in the cytoplasm, as well as in the nucleus; however, the nucleoli were excluded. This protein was scattered around the nuclei, and the distribution might reflect association with the so-called nuclear bodies PMID: 12479870
9. Recombinant fusion protein GST.P0 expressed in insect cells, but not the protein obtained in Escherichia coli, had the ability to form a complex with P1 and P2 proteins. PMID: 15336536
10. P0 overexpression may cause tumorigenesis in breast and liver tissues at least in part by inhibiting GCIP-mediated tumor suppression. PMID: 17621266
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亞細胞定位：

Nucleus. Cytoplasm.
蛋白家族：

Universal ribosomal protein uL10 family
數據庫鏈接：

HGNC: 10371

OMIM: 180510

KEGG: hsa:6175

STRING: 9606.ENSP00000339027

UniGene: Hs.546285

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