RPL26 Antibody

中文名稱：

RPL26兔多克隆抗體
貨號：

CSB-PA020207LA01HU
規格：

￥440
圖片：
Immunofluorescent analysis of HepG2 cells using CSB-PA020207LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

IHC image of CSB-PA020207LA01HU diluted at 1:600 and staining in paraffin-embedded human ovarian cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) RPL26 Polyclonal antibody
Uniprot No.：

P61254
基因名：

RPL26
別名：

tibody; 60S ribosomal protein L26 antibody; 60S ribosomal protein L26 like 1 antibody; DBA11 antibody; FLJ46904 antibody; L26 antibody; OTTHUMP00000135333 antibody; PTB associated splicing factor antibody; Ribosomal protein L26 antibody; Ribosomal protein L26 homolog antibody; Ribosomal protein L26 like 1 antibody; Ribosomal protein L26 pseudogene 1 antibody; RL26_HUMAN antibody; rpl26 antibody; RPL26P1 antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human 60S ribosomal protein L26 protein (48-143AA)
免疫原種屬：

Homo sapiens (Human)

標記方式：

Non-conjugated

本頁面中的產品，RPL26 Antibody (CSB-PA020207LA01HU)，的標記方式是Non-conjugated。對于RPL26 Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA020207LB01HU	RPL26 Antibody, HRP conjugated	ELISA
FITC	CSB-PA020207LC01HU	RPL26 Antibody, FITC conjugated
Biotin	CSB-PA020207LD01HU	RPL26 Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA, IHC, IF

推薦稀釋比：

Application	Recommended Dilution
IHC	1:500-1:1000
IF	1:50-1:200

Protocols：

ELISA Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

功能：

Component of the large ribosomal subunit.
基因功能參考文獻：
1. ionizing radiation (IR) inhibits the activity of SMG1, a phosphoinositide-3-kinase-like kinase family member, reducing the binding of SMG1 to a specific region near exon 9 of p53 precursor mRNA and promoting the binding of ribosomal protein L26 (RPL26) to p53 pre-mRNA PMID: 28288992
2. In colorectal tumor cells RPL26 regulates p73 expression via two distinct mechanisms: protein stability and mRNA translation. PMID: 27825141
3. Six1 regulates p53 via a dual mechanism involving upregulation of microRNA-27a and downregulation of RPL26. PMID: 26687066
4. The results showed that knockdown of RPL26 or RPL29 expression significantly suppressed cell proliferation, induced cell arrest at G0/G1 phase and enhanced cell apoptosis PMID: 22868929
5. Northern Blot Together with RPL5, RPL11, and RPS7, RPL26 is the fourth RP regulating p53 activity that is linked to diamond-blackfan anemia. PMID: 22431104
6. suggest a model in which the base pairings in the p53 UTR interaction regions are critical for both translational repression and stress induction of p53 by NCL and RPL26 PMID: 22433872
7. Mdm2 binds L26 and drives its polyubiquitylation and proteasomal degradation. PMID: 18951086
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相關疾?。?/div>
Diamond-Blackfan anemia 11 (DBA11)
蛋白家族：

Universal ribosomal protein uL24 family
數據庫鏈接：

HGNC: 10327

OMIM: 603704

KEGG: hsa:6154

STRING: 9606.ENSP00000293842

UniGene: Hs.482144

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