RNMTL1 Antibody

說明書

產品詳情

Uniprot No.：

Q9HC36
基因名：

MRM3
別名：

16S rRNA (guanosine(1370)-2'-O)-methyltransferase antibody; 16S rRNA [Gm1370] 2'-O-methyltransferase antibody; 4833420N02Rik antibody; AI255153 antibody; FLJ10581 antibody; HC90 antibody; MRM3 antibody; MRM3_HUMAN antibody; Putative RNA methyltransferase antibody; RMTL1 antibody; RNA methyltransferase like 1 antibody; RNA methyltransferase like protein 1 antibody; RNA methyltransferase-like protein 1 antibody; RP23-147P4.7 antibody; rRNA methyltransferase 3, mitochondrial antibody
宿主：

Rabbit
反應種屬：

Human,Mouse,Rat
免疫原：

Human RNMTL1
免疫原種屬：

Homo sapiens (Human)
抗體亞型：

IgG
純化方式：

Antigen Affinity purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
產品提供形式：

Liquid
應用范圍：

ELISA,WB,IHC
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
Immunohistochemistry (IHC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

S-adenosyl-L-methionine-dependent 2'-O-ribose methyltransferase that catalyzes the formation of 2'-O-methylguanosine at position 1370 (Gm1370) in the 16S mitochondrial large subunit ribosomal RNA (mtLSU rRNA), a conserved modification in the peptidyl transferase domain of the mtLSU rRNA.
基因功能參考文獻：
1. MRM2 and MRM3 are human mitochondrial methyltransferases involved in the modification of 16S rRNA and are important factors for the biogenesis and function of the large subunit of the mitochondrial ribosome. PMID: 25009282
2. Data show that 2'-O-methyltransferases MRM1, MRM2, and RNMTL1 are responsible for modification of large subunit rRNA at residues G1145, U1369, and G1370, respectively. PMID: 25074936
3. The ATF/CREB site is the key element for transcription of this protein found on human chromosome 17. PMID: 12296377
亞細胞定位：

Mitochondrion.
蛋白家族：

Class IV-like SAM-binding methyltransferase superfamily, RNA methyltransferase TrmH family
組織特異性：

Expressed at same level in normal liver and hepatocarcinoma.
數據庫鏈接：

HGNC: 18485

OMIM: 612600

KEGG: hsa:55178

STRING: 9606.ENSP00000306080

UniGene: Hs.182729

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