RMND5A Antibody

中文名稱：

RMND5A兔多克隆抗體
貨號：

CSB-PA875693LA01HU
規格：

￥440
圖片：
Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA875693LA01HU at dilution of 1:100
其他：

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) RMND5A Polyclonal antibody
Uniprot No.：

Q9H871
基因名：

RMND5A
別名：

RMND5A antibody; E3 ubiquitin-protein transferase RMND5A antibody; EC 2.3.2.27 antibody; P44CTLH antibody; Protein RMD5 homolog A antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Protein RMD5 homolog A protein (1-391AA)
免疫原種屬：

Homo sapiens (Human)

標記方式：

Non-conjugated

本頁面中的產品，RMND5A Antibody (CSB-PA875693LA01HU)，的標記方式是Non-conjugated。對于RMND5A Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA875693LB01HU	RMND5A Antibody, HRP conjugated	ELISA
FITC	CSB-PA875693LC01HU	RMND5A Antibody, FITC conjugated
Biotin	CSB-PA875693LD01HU	RMND5A Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA, IHC

推薦稀釋比：

Application	Recommended Dilution
IHC	1:20-1:200

Protocols：

ELISA Protocol
Immunohistochemistry (IHC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Core component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1. MAEA and RMND5A are both required for catalytic activity of the CTLH E3 ubiquitin-protein ligase complex. Catalytic activity of the complex is required for normal cell proliferation. The CTLH E3 ubiquitin-protein ligase complex is not required for the degradation of enzymes involved in gluconeogenesis, such as FBP1.
基因功能參考文獻：
1. Duplications of this region involving RMND5A, whose product contains a C-terminal to lis homology (LisH) domain, have not previously been associated with a defined phenotype but may present insight into encephalocele formation. PMID: 22681319
2. RanBPM, ARMC8alpha, ARMC8beta, Muskelin, p48EMLP, and p44CTLH form complexes in cells. PMID: 17467196
亞細胞定位：

Nucleus, nucleoplasm. Cytoplasm.
數據庫鏈接：

HGNC: 25850

KEGG: hsa:64795

STRING: 9606.ENSP00000283632

UniGene: Hs.424184

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