RINT1 Antibody, HRP conjugated
-
中文名稱：RINT1兔多克隆抗體, HRP偶聯
-
貨號：CSB-PA747351LB01HU
-
規格：￥880
-
其他：
產品詳情
-
產品名稱：Rabbit anti-Homo sapiens (Human) RINT1 Polyclonal antibody
-
Uniprot No.：
-
基因名：RINT1
-
別名：DKFZp667H2324 antibody; FLJ11785 antibody; HsRINT 1 antibody; HsRINT-1 antibody; HsRINT1 antibody; RAD50 interacting protein 1 antibody; RAD50 interactor 1 antibody; RAD50-interacting protein 1 antibody; RINT 1 antibody; RINT-1 antibody; RINT1 antibody; RINT1_HUMAN antibody
-
宿主：Rabbit
-
反應種屬：Human
-
免疫原：Recombinant Human RAD50-interacting protein 1 protein (401-700AA)
-
免疫原種屬：Homo sapiens (Human)
-
標記方式：HRP
-
克隆類型：Polyclonal
-
抗體亞型：IgG
-
純化方式：>95%, Protein G purified
-
濃度：It differs from different batches. Please contact us to confirm it.
-
保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 -
產品提供形式：Liquid
-
應用范圍：ELISA
-
Protocols：
-
儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
-
用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
-
功能：Involved in regulation of membrane traffic between the Golgi and the endoplasmic reticulum (ER); the function is proposed to depend on its association in the NRZ complex which is believed to play a role in SNARE assembly at the ER. May play a role in cell cycle checkpoint control. Essential for telomere length control.
-
基因功能參考文獻：
- Study presents evidence that in the Caucasian population, RINT1 does not represent a moderate- penetrance breast cancer susceptibility gene, and find no evidence to support an association of RINT1 mutation with Lynch syndrome-related cancer incidence in breast cancer families. PMID: 27544226
- these data are more consistent with the hypothesis that RINT1 functions as an oncogene rather than a tumor suppressor gene in the context of colorectal cancer. PMID: 28264000
- HPV E2 protein targets Rad50-interacting protein 1 (Rint1) to facilitate virus genome replication. PMID: 28031358
- RINT-1 interacts with MSP58 and UBF within nucleoli and plays a role in ribosomal gene transcription. PMID: 27530925
- Results suggest that high RAD50 interactor 1 (RINT1) expression may represent a risk factor for low-grade gliomas (LGGs)-related seizures. PMID: 25304616
- Results identified RINT1 as a putative breast cancer predisposition gene that also seems to be associated with risk for a spectrum of other cancers similar to those that have previously been described for Lynch syndrome. PMID: 25050558
- RINT-1 is also required for endosome-to-trans-Golgi network trafficking. PMID: 23885118
- RINT1 was validated as a novel glioblastoma oncogene PMID: 23074196
- These findings suggest that RINT-1 serves as a novel tumor suppressor essential for maintaining the dynamic integrity of the Golgi apparatus and the centrosome, a prerequisite to their proper coordination during cell division. PMID: 17470549
- Rab6 regulates distinct Golgi trafficking pathways involving two separate protein complexes: ZW10/RINT-1 and COG. PMID: 17699596
顯示更多
收起更多
-
亞細胞定位：Cytoplasm. Endoplasmic reticulum membrane; Peripheral membrane protein.
-
蛋白家族：RINT1 family
-
數據庫鏈接：
Most popular with customers
-
-
YWHAB Recombinant Monoclonal Antibody
Applications: ELISA, WB, IHC, IF, FC
Species Reactivity: Human, Mouse, Rat
-
Phospho-YAP1 (S127) Recombinant Monoclonal Antibody
Applications: ELISA, WB, IHC
Species Reactivity: Human
-
-
-
-
-
