RGS22 Antibody

說明書

中文名稱：

RGS22兔多克隆抗體
貨號：

CSB-PA276672
規格：

￥1100
圖片：
The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using CSB-PA276672(RGS22 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: ×200)

The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using CSB-PA276672(RGS22 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: ×200)
其他：

產品詳情

Uniprot No.：

Q8NE09
基因名：

RGS22
別名：

FLJ40080 antibody; FLJ75004 antibody; MGC102908 antibody; PRTD-NY2 antibody; Regulator of G-protein signaling 22 antibody; RGS22 antibody; RGS22_HUMAN antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Fusion protein of Human RGS22
免疫原種屬：

Homo sapiens (Human)
標記方式：

Non-conjugated
抗體亞型：

IgG
純化方式：

Antigen affinity purification
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
產品提供形式：

Liquid
應用范圍：

ELISA,IHC

推薦稀釋比：

Application	Recommended Dilution
ELISA	1:2000-1:5000
IHC	1:25-1:100

Protocols：

ELISA Protocol
Immunohistochemistry (IHC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form.
基因功能參考文獻：
1. Regulator of G-protein signaling 22 (RGS22) was identified as a direct target of miR-1260b and was inhibited by miR-1260b. Knockdown of RGS22 increased proliferation of hepatocellular carcinoma cells. PMID: 29038925
2. New basal cell carcinoma susceptibility loci were identified at TGM3 (rs214782) and RGS22(rs7006527). PMID: 24403052
3. Over-expression of RGS22 in a highly metastatic esophageal cancer cell line causes decrease in cell migration and reduction in the invasive potential of the cells. PMID: 21533872
亞細胞定位：

Cytoplasm. Nucleus. Note=Expressed in the cytoplasm of spermatogonia and spermatocytes. In spermatids, also expressed in the nucleus.
組織特異性：

Testis-specific. Expressed in Leydig cells and spermatogenic cells from the spermatogonia to spermatid stages (at protein level).
數據庫鏈接：

HGNC: 24499

OMIM: 615650

KEGG: hsa:26166

STRING: 9606.ENSP00000354109

UniGene: Hs.120021

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