RBMS3 Antibody

中文名稱：

RBMS3兔多克隆抗體
貨號：

CSB-PA761548LA01HU
規格：

￥440
圖片：
Immunofluorescence staining of HepG2 cells with CSB-PA761548LA01HU at 1:300, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
其他：

產品詳情
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靶點詳情

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) RBMS3 Polyclonal antibody
Uniprot No.：

Q6XE24
基因名：

RBMS3
別名：

RBMS3 antibody; RNA-binding motif antibody; single-stranded-interacting protein 3 antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human RNA-binding motif, single-stranded-interacting protein 3 protein (372-437AA)
免疫原種屬：

Homo sapiens (Human)

標記方式：

Non-conjugated

本頁面中的產品，RBMS3 Antibody (CSB-PA761548LA01HU)，的標記方式是Non-conjugated。對于RBMS3 Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA761548LB01HU	RBMS3 Antibody, HRP conjugated	ELISA
FITC	CSB-PA761548LC01HU	RBMS3 Antibody, FITC conjugated
Biotin	CSB-PA761548LD01HU	RBMS3 Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA, IF

推薦稀釋比：

Application	Recommended Dilution
IF	1:200-1:500

Protocols：

ELISA Protocol
Immunofluorescence (IF) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

功能：

Binds poly(A) and poly(U) oligoribonucleotides.
基因功能參考文獻：
1. RBMS3 inhibited the proliferation and tumorigenesis of breast cancer cells, at least in part, through inactivation of the Wnt/beta-catenin signaling pathway PMID: 28409548
2. These findings implicated that RBMS3 and nuclear HIF1A could act as prognostic biomarkers and therapeutic targets for GC. PMID: 27902480
3. We identified rs117026326 on GTF2I with GWAS significance (P = 1.10 x 10(-15)) and rs13079920 on RBMS3 with suggestive significance (P = 2.90 x 10(-5)) associating with Primary Sjogren's syndrome in women. PMID: 27503288
4. one interacting gene pair (RBMS3 versus ZNF516) which, even after Bonferroni correction for multiple testing, showed consistently significant effects on hip bone mineral density. PMID: 23045156
5. RBMS3 is a novel tumor suppressor gene in lung squamous cell carcinoma PMID: 25588924
6. RBMS3 at 3p24 inhibits nasopharyngeal carcinoma development via inhibiting cell proliferation, angiogenesis, and inducing apoptosis PMID: 22957092
7. genetic susceptibility plays a role in the pathophysiology of Bisphosphonate-related osteonecrosis of the jaw (BRONJ), with RBMS3 having a significant effect in the risk. PMID: 22267851
8. a tumor suppression function for the human RBMS3 gene in esophageal squamous cell carcinoma, acting through c-Myc downregulation, with genetic loss of this gene contributing to poor outcomes in disease PMID: 21844183
9. These results suggest that RBMS3, by binding Prx1 mRNA in a sequence-specific manner, controls Prx1 expression and indirectly collagen synthesis. PMID: 17586524
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亞細胞定位：

Cytoplasm.
組織特異性：

Expressed in fetal brain, fetal lung, fetal liver, heart, brain, placenta, lung, liver, muscle, kidney and pancreas.
數據庫鏈接：

HGNC: 13427

OMIM: 605786

KEGG: hsa:27303

STRING: 9606.ENSP00000373277

UniGene: Hs.221436

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