RAD54B Antibody, Biotin conjugated
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中文名稱：RAD54B兔多克隆抗體, Biotin偶聯(lián)
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貨號：CSB-PA896748LD01HU
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規(guī)格：￥880
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) RAD54B Polyclonal antibody
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Uniprot No.：
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基因名：RAD54B
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別名：RAD54B antibody; DNA repair and recombination protein RAD54B antibody; EC 3.6.4.- antibody; RAD54 homolog B antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Recombinant Human DNA repair and recombination protein RAD54B protein (1-167AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：Biotin
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 -
產品提供形式：Liquid
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應用范圍：ELISA
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Involved in DNA repair and mitotic recombination. May play an active role in recombination processes in concert with other members of the RAD52 epistasis group.
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基因功能參考文獻：
- High RAD54B expression is associated with hepatoma. PMID: 29956808
- Review of structural aspects of RAD54B, molecular functions associated with its cellular roles in preventing genome instability, and how aberrant function contributes to oncogenesis. PMID: 28295846
- RAD54B expression has potential to serve as a novel prognostic biomarker, particularly for distant recurrence in colorectal cancer PMID: 26046797
- Patients with expression of both FEN1 and RAD54B were prone to have advanced nodal involvement and significantly poor prognosis. PMID: 26431531
- The scaffolding function of Rad54B dynamically regulates the maintenance of genome integrity by limiting checkpoint strength. PMID: 25384516
- support a model in which RAD54L and RAD54B counteract genome-destabilizing effects of direct binding of RAD51 to dsDNA in tumor cells PMID: 25765654
- RAD54B-deficient cells are selectively killed relative to controls via siRNA-based silencing of SOD1 PMID: 24002644
- RAD54B and GREB1 gene polymorphisms may not be associated with PCOS in the Han Chinese population. PMID: 23876972
- These results suggest that hINO80 assists double-strand break repair by positively regulating the expression of the Rad54B and XRCC3 genes. PMID: 20687897
- Rad54B is a DNA-dependent ATPase and has biochemical properties different from its structural homolog in yeast, Tid1/Rdh54 PMID: 11884632
- Rad54B enhanced the DNA strand-exchange activity of Dmc1 by stabilizing the Dmc1-single-stranded DNA complex. PMID: 16945962
- the loss of heterozygosity (LOH) in the 8q12-q24.1 chromosomal region, containing RAD54B gene isn't predictive for breast cancer PMID: 17585536
- S100A11 targets Rad54B to sites of DNA DSB repair sites and has a role in p21-based regulation of cell cycle PMID: 18463164
- RAD54B binding may affect the quaternary structure of DMC1. PMID: 18718930
- RAD54B-deficient human colorectal cancer cells are sensitive to synthetic lethal killing by reduced FEN1 expression, while isogenic RAD54B proficient cells are not PMID: 19218431
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亞細胞定位：Nucleus.
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蛋白家族：SNF2/RAD54 helicase family
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組織特異性：Abundantly expressed in testis and spleen. Relatively low levels observed in thymus, prostate, ovary and colon.
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數(shù)據(jù)庫鏈接：
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