RAB2A Antibody
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中文名稱：RAB2A兔多克隆抗體
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貨號：CSB-PA040134
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規(guī)格：￥1090
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圖片：
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Western Blot analysis of A549 cells using Rab 2A Polyclonal Antibody
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其他：
產(chǎn)品詳情
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Uniprot No.：
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基因名：
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別名：9330148M11Rik antibody; C80220 antibody; GTP binding protein antibody; LHX antibody; OTTMUSP00000004796 antibody; RAB2 antibody; RAB2 member RAS oncogene family antibody; RAB2A antibody; RAB2A; member RAS oncogene family antibody; RAB2A_HUMAN antibody; Ras related protein Rab 2A antibody; RAS-associated protein RAB2 antibody; Ras-related protein Rab-2A antibody; RP23-183L6.1 antibody; Small GTP binding protein RAB2A antibody
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宿主：Rabbit
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反應(yīng)種屬：Human,Mouse,Rat
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免疫原：Synthesized peptide derived from the Internal region of Human Rab 2A.
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免疫原種屬：Homo sapiens (Human)
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標(biāo)記方式：Non-conjugated
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抗體亞型：IgG
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純化方式：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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產(chǎn)品提供形式：Liquid
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應(yīng)用范圍：WB, IHC, ELISA
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推薦稀釋比：
Application Recommended Dilution WB 1:500-1:2000 IHC 1:100-1:300 ELISA 1:20000 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評價
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靶點詳情
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功能：Required for protein transport from the endoplasmic reticulum to the Golgi complex.
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基因功能參考文獻(xiàn)：
- S100A7 affects cell motility and invasion by regulating the RAB2A-associated MAPK signaling cascades. PMID: 27767088
- Identify Rab2 as a key factor for autophagic and endocytic cargo delivery to and degradation in lysosomes. PMID: 28483915
- our data reveal that RAB2A is new critical membrane trafficking players in the regulation of mesenchymal properties of normal and tumorigenic cells and a critical determinant of an invasive, proteolytic mode of BC progression. PMID: 27255086
- RAB2A variance has effect on the structure and function of the PFC and related cognitive functions. PMID: 26249043
- This study demonstrated that RAB2A mutation showing the highest statistical significance in Autism and Schizophrenia. PMID: 26938441
- The immunohistochemistry-based validation using tissue microarray slides in oral squamous cell carcinoma revealed overexpression of the RAB2A and PRDX1 gene in 80 and 68 % of the tested clinical cases, respectively. PMID: 26159854
- Pin1/Rab2A/Erk drives BCSC expansion and tumorigenicity, suggesting potential drug targets. PMID: 25818297
- As a result of the translocations, RAB2A-PLAG1, the constitutively active promoter of the partner gene drives the ectopic expression of PLAG1. PMID: 24700772
- first X-ray crystal structure of RicA to 2.7 A resolution and have quantified the affinity of RicA binding to human Rab2 in its GDP-bound and nucleotide-free forms PMID: 24251537
- The authors identified a specific interaction between the human small GTPase Rab2 and a Brucella spp. protein named RicA. PMID: 21501366
- The results of this study provided that RAB2A and SLC38A1, were associated with the density of calbindin-positive neurons and the number of perineuronal oligodendrocytes in psychiatric disorders. PMID: 20308991
- Rab2 interacts directly with atypical protein kinase C iota/lambda and inhibits aPKCiota/lambda-dependent GADPH phosphorylation PMID: 14570876
- These data demonstrate that Rab2 and Rab6 differentially influence anterograde transport and signaling of GPCRs. PMID: 17716866
- ICA69 as a novel Rab2 effector and its role in regulating the early transport of insulin secretory granule proteins PMID: 18187231
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亞細(xì)胞定位：Endoplasmic reticulum-Golgi intermediate compartment membrane; Lipid-anchor. Melanosome. Endoplasmic reticulum membrane; Lipid-anchor. Golgi apparatus membrane; Lipid-anchor. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
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蛋白家族：Small GTPase superfamily, Rab family
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數(shù)據(jù)庫鏈接：
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