RAB11FIP5 Antibody

中文名稱：

RAB11FIP5兔多克隆抗體
貨號：

CSB-PA863141LA01HU
規格：

￥440
圖片：
IHC image of CSB-PA863141LA01HU diluted at 1:400 and staining in paraffin-embedded human kidney tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

IHC image of CSB-PA863141LA01HU diluted at 1:400 and staining in paraffin-embedded human placenta tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
其他：

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) RAB11FIP5 Polyclonal antibody
Uniprot No.：

Q9BXF6
基因名：

RAB11FIP5
別名：

GAF 1 antibody; Gaf-1 antibody; GAF1 antibody; gamma SNAP associated factor 1 antibody; Gamma-SNAP-associated factor 1 antibody; KIAA0857 antibody; Phosphoprotein pp75 antibody; pp75 antibody; RAB11 family interacting protein 5 (class I) antibody; Rab11 family-interacting protein 5 antibody; Rab11 FIP5 antibody; Rab11 interacting protein antibody; Rab11 interacting protein Rip11 antibody; Rab11-FIP5 antibody; Rab11-interacting protein Rip11 antibody; Rab11fip5 antibody; RFIP5_HUMAN antibody; RIP11 antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Rab11 family-interacting protein 5 protein (374-545AA)
免疫原種屬：

Homo sapiens (Human)

標記方式：

Non-conjugated

本頁面中的產品，RAB11FIP5 Antibody (CSB-PA863141LA01HU)，的標記方式是Non-conjugated。對于RAB11FIP5 Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA863141LB01HU	RAB11FIP5 Antibody, HRP conjugated	ELISA
FITC	CSB-PA863141LC01HU	RAB11FIP5 Antibody, FITC conjugated
Biotin	CSB-PA863141LD01HU	RAB11FIP5 Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA, IHC

推薦稀釋比：

Application	Recommended Dilution
IHC	1:200-1:500

Protocols：

ELISA Protocol
Immunohistochemistry (IHC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Rab effector involved in protein trafficking from apical recycling endosomes to the apical plasma membrane. Involved in insulin granule exocytosis. May regulate V-ATPase intracellular transport in response to extracellular acidosis.
基因功能參考文獻：
1. FIP5-T276 phosphorylation occurs specifically during metaphase and anaphase. PMID: 24591568
2. FIP5-SNX18 complex plays a pivotal role in the polarized transport of apical proteins during apical lumen initiation in epithelial cells. PMID: 21969467
3. These data introduce Rab11b as a crucial regulator and Rip11 as mediator of acidosis-induced V-ATPase traffic in duct cells of submandibular gland. PMID: 20717956
4. analysis of the rearrangement breakpoints suggests that the reciprocal translocation may have formed secondary to incorrect repair of double strand breaks (DSBs) by nonhomologous end-joining (NHEJ). PMID: 18384058
亞細胞定位：

Cytoplasm. Recycling endosome membrane; Peripheral membrane protein. Early endosome membrane; Peripheral membrane protein. Golgi apparatus membrane; Peripheral membrane protein. Cytoplasmic vesicle, secretory vesicle membrane; Peripheral membrane protein. Mitochondrion membrane; Peripheral membrane protein.
組織特異性：

Detected at low levels in heart, brain, placenta, lung, liver, adipocytes, kidney, spleen, skeletal muscle and pancreas.
數據庫鏈接：

HGNC: 24845

OMIM: 605536

KEGG: hsa:26056

STRING: 9606.ENSP00000258098

UniGene: Hs.24557

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