PSMA5 Antibody, FITC conjugated

說明書

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) PSMA5 Polyclonal antibody
Uniprot No.：

P28066
基因名：

PSMA5
別名：

Macropain zeta chain antibody; Multicatalytic endopeptidase complex zeta chain antibody; Proteasome (prosome macropain) subunit alpha type 5 antibody; Proteasome alpha5 subunit antibody; Proteasome component 5 antibody; Proteasome subunit alpha type 5 antibody; Proteasome subunit alpha type-5 antibody; Proteasome subunit zeta antibody; Proteasome zeta chain antibody; PSA5_HUMAN antibody; PSC5 antibody; PSMA5 antibody; ZETA antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Proteasome subunit alpha type-5 protein (124-180AA)
免疫原種屬：

Homo sapiens (Human)
標記方式：

FITC
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產品提供形式：

Liquid
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex).
基因功能參考文獻：
1. Selective upregulation of the ubiquitin-proteasome proteolytic pathway proteins, proteasome zeta chain and isopeptidase T in fetal Down syndrome. PMID: 11771738
亞細胞定位：

Cytoplasm. Nucleus.
蛋白家族：

Peptidase T1A family
組織特異性：

Expressed in fetal brain (at protein level).
數據庫鏈接：

HGNC: 9534

OMIM: 176844

KEGG: hsa:5686

STRING: 9606.ENSP00000271308

UniGene: Hs.485246

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