PPP2R3A Antibody

中文名稱：

PPP2R3A兔多克隆抗體
貨號：

CSB-PA21129A0Rb
規格：

￥440
圖片：
Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA21129A0Rb at dilution of 1:100

Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA21129A0Rb at dilution of 1:100
其他：

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) PPP2R3A Polyclonal antibody
Uniprot No.：

Q06190
基因名：

PPP2R3A
別名：

AI118493 antibody; DNA for thyroid hormone receptor binding site (258bp) antibody; P2R3A_HUMAN antibody; PP2A subunit B B''-PR72/PR130 antibody; PP2A subunit B B72/B130 isoforms antibody; PP2A subunit B isoform PR72/PR130 antibody; PP2A subunit B isoform R3 isoform antibody; PP2A subunit B isoforms B''-PR72/PR130 antibody; PP2A subunit B isoforms B72/B130 antibody; PP2A subunit B PR72/PR130 isoforms antibody; PP2A subunit B R3 isoform antibody; PPP2R3 antibody; Ppp2r3a antibody; PR130 antibody; PR59 antibody; PR72 antibody; Protein phosphatase 2 (formerly 2A) regulatory subunit B'' alpha antibody; Serine/threonine protein phosphatase 2A 72/130 kDa regulatory subunit B antibody; Serine/threonine-protein phosphatase 2A 72/130 kDa regulatory subunit B antibody; Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha protein (256-508AA)
免疫原種屬：

Homo sapiens (Human)

標記方式：

Non-conjugated

本頁面中的產品，PPP2R3A Antibody (CSB-PA21129A0Rb)，的標記方式是Non-conjugated。對于PPP2R3A Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA21129B0Rb	PPP2R3A Antibody, HRP conjugated	ELISA
FITC	CSB-PA21129C0Rb	PPP2R3A Antibody, FITC conjugated
Biotin	CSB-PA21129D0Rb	PPP2R3A Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA, IHC

推薦稀釋比：

Application	Recommended Dilution
IHC	1:20-1:200

Protocols：

ELISA Protocol
Immunohistochemistry (IHC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.
基因功能參考文獻：
1. HDAC1 and HDAC2 suppress the expression of PPP2R3A/PR130, a regulatory subunit of the trimeric serine/threonine phosphatase 2 (PP2A). PMID: 29472538
2. this study shows the importance of PP2A complexes with the LIM domains of lipoma-preferred partner in cell adhesion and migration dynamics PMID: 26945059
3. two Ca2+-binding EF-hand motifs in the B"/PR72 subunit of protein phosphatase 2A demonstrating the ability or calcium ions to interact with and regulate PP2A PMID: 12524438
4. The B''/PR72 subunit mediates Ca2+-dependent dephosphorylation of DARPP-32 by protein phosphatase 2A. PMID: 17535922
5. PP2A can be targeted in a calcium-regulated manner to Cdc6 via the PR70 subunit, where it plays a role in regulating protein phosphorylation and stability. PMID: 18397887
6. PR72 interacts physically and functionally with Naked cuticle. PR72, like Naked cuticle, acts as a negative regulator of the classical Wnt signaling cascade. PMID: 15687260
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組織特異性：

Expressed in heart, brain, placenta, lung, muscle and kidney.
數據庫鏈接：

HGNC: 9307

OMIM: 604944

KEGG: hsa:5523

STRING: 9606.ENSP00000264977

UniGene: Hs.518155

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