PPP1R9A Antibody

說明書

產(chǎn)品詳情

Uniprot No.：

Q9ULJ8
基因名：

PPP1R9A
別名：

FLJ20068 antibody; KIAA1222 antibody; NEB1_HUMAN antibody; Neurabin I antibody; Neurabin-1 antibody; Neurabin-I antibody; Neurabin1 antibody; NeurabinI antibody; Neural tissue specific F actin binding protein I antibody; Neural tissue-specific F-actin-binding protein I antibody; NRB 1 antibody; NRB I antibody; NRB1 antibody; NRBI antibody; Ppp1r9a antibody; Protein phosphatase 1 regulatory (inhibitor) subunit 9A antibody; Protein phosphatase 1 regulatory subunit 9A antibody
宿主：

Rabbit
反應(yīng)種屬：

Human,Mouse,Rat
免疫原：

Human PPP1R9A
免疫原種屬：

Homo sapiens (Human)
抗體亞型：

IgG
純化方式：

Antigen Affinity purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

ELISA,WB,IF
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
Immunofluorescence (IF) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Binds to actin filaments (F-actin) and shows cross-linking activity. Binds along the sides of the F-actin. May be involved in neurite formation. Inhibits protein phosphatase 1-alpha activity.
基因功能參考文獻：
1. MARCKS and PPP1R9A might contribute to spine loss in schizophrenia and bipolar disorder through their interactions. PMID: 25757715
2. CHN2, ABCB1 and PPP1R9A expression on chromosome 7 is implicated in the pathogenesis of hepatosplenic T-cell lymphoma distinguishing it from other malignancies. PMID: 25057852
3. Studies suggest that any change in substrate specificity of the spinophilin : PP1 holoenzyme complex was probably due to direct modification of a PP1 substrate binding surface. PMID: 22284538
4. PPP1R9A gene is imprinted, with preferential expression from the maternal allele in embryonic skeletal muscle and extra-embryonic tissues, but biallelic expression in other embryonic tissues. PMID: 15286155
亞細胞定位：

Cytoplasm, cytoskeleton. Cell junction, synapse, synaptosome.
數(shù)據(jù)庫鏈接：

HGNC: 14946

OMIM: 602468

KEGG: hsa:55607

STRING: 9606.ENSP00000405514

UniGene: Hs.21816

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