PPA2 Antibody
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中文名稱：PPA2兔多克隆抗體
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貨號：CSB-PA867137LA01HU
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規格：￥440
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圖片：
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Western Blot
Positive WB detected in: Hela whole cell lysate, Rat kidney tissue, Rat liver tissue, Mouse kidney tissue, Mouse liver tissue
All lanes: PPA2 antibody at 3.1µg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 38, 40, 35, 19, 26 kDa
Observed band size: 38 kDa -
IHC image of CSB-PA867137LA01HU diluted at 1:200 and staining in paraffin-embedded human prostate tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) PPA2 Polyclonal antibody
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Uniprot No.：
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基因名：
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別名：HSPC124 antibody; Inorganic pyrophosphatase 2 antibody; Inorganic pyrophosphatase 2, mitochondrial antibody; IPYR2_HUMAN antibody; mitochondrial antibody; Ppa2 antibody; PPase 2 antibody; PPase2 antibody; Pyrophosphatase (inorganic) 2 antibody; Pyrophosphatase SID6 306 antibody; Pyrophosphatase SID6-306 antibody; Pyrophosphate phospho-hydrolase 2 antibody; SID6 306 antibody
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宿主：Rabbit
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反應種屬：Human, Mouse, Rat
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免疫原：Recombinant Human Inorganic pyrophosphatase 2, mitochondrial protein (180-298AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
本頁面中的產品，PPA2 Antibody (CSB-PA867137LA01HU)，的標記方式是Non-conjugated。對于PPA2 Antibody，我們還提供其他標記。見下表：
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 -
產品提供形式：Liquid
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應用范圍：ELISA, WB, IHC
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推薦稀釋比：
Application Recommended Dilution WB 1:500-1:5000 IHC 1:200-1:500 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Hydrolyzes inorganic pyrophosphate. This activity is essential for correct regulation of mitochondrial membrane potential, and mitochondrial organization and function.
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基因功能參考文獻：
- findings confirm the pathogenicity of PPA2 mutations and suggest that PPA2 is a cardiomyopathy-associated protein, which has a greater physiological importance in mitochondrial function than previously recognized PMID: 27523597
- data demonstrate that PPA2 is an essential gene in yeast and that biallelic mutations in PPA2 cause a mitochondrial disease leading to sudden cardiac arrest in infants PMID: 27523598
- Single nucleotide polymorphisms in PPA2 is associated with response to antipsychotic agents in schizophrenia. PMID: 23241943
- We think that PP2A can be one of the key components to regulate the fusion of various endocytotic compartments and /or the trafficking along the microtubules. PMID: 19067239
- No pathogenic mutations were identified in the PPA2 gene in patients with mitochondrial DNA depletion syndromes (MDS). PMID: 16300924
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相關疾病：Sudden cardiac failure, alcohol-induced (SCFAI); Sudden cardiac failure, infantile (SCFI)
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亞細胞定位：Mitochondrion.
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蛋白家族：PPase family
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組織特異性：Detected in brain, gastric carcinoma, lung, ovary, skeletal muscle, umbilical cord blood and a cell line derived from kidney proximal tubule epithelium.
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數據庫鏈接：
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