POLR3K Antibody

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) POLR3K Polyclonal antibody
Uniprot No.：

Q9Y2Y1
基因名：

POLR3K
別名：

C11 antibody; C11 RNP3 antibody; DNA directed RNA polymerase III subunit K antibody; DNA directed RNA polymerase III subunit RPC10 antibody; DNA directed RNA polymerases III 12.5 kDa polypeptide antibody; DNA-directed RNA polymerase III subunit K antibody; DNA-directed RNA polymerase III subunit RPC10 antibody; hRPC11 antibody; HsC11p antibody; My010 antibody; POLR3K antibody; Polymerase (RNA) III (DNA directed) polypeptide K antibody; Polymerase (RNA) III (DNA directed) polypeptide K; 12.3 kDa antibody; RNA polymerase III 12.5 kDa subunit antibody; RNA polymerase III subunit (hRPC11) antibody; RNA polymerase III subunit C10 antibody; RNA polymerase III subunit C11 antibody; RNA polymerase III subunit CII antibody; RPC10 antibody; RPC10_HUMAN antibody; RPC11 antibody; RPC12.5 antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human DNA-directed RNA polymerase III subunit RPC10 protein (1-108AA)
免疫原種屬：

Homo sapiens (Human)

標記方式：

Non-conjugated

本頁面中的產品，POLR3K Antibody (CSB-PA018352HA01HU)，的標記方式是Non-conjugated。對于POLR3K Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA018352HB01HU	POLR3K Antibody, HRP conjugated	ELISA
FITC	CSB-PA018352HC01HU	POLR3K Antibody, FITC conjugated
Biotin	CSB-PA018352HD01HU	POLR3K Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF- Kappa-B through the RIG-I pathway.
基因功能參考文獻：
1. Results from a study on gene expression variability markers in early-stage human embryos shows that POLR3K is a putative expression variability marker for the 3-day, 8-cell embryo stage. PMID: 26288249
2. Changes in Maf1 expression affect Pol III-dependent transcription in human glioblastoma lines. PMID: 17499043
亞細胞定位：

Nucleus, nucleolus.
蛋白家族：

Archaeal RpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family
數據庫鏈接：

HGNC: 14121

OMIM: 606007

KEGG: hsa:51728

STRING: 9606.ENSP00000293860

UniGene: Hs.632223

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