PMPCA Antibody

說明書

中文名稱：

PMPCA兔多克隆抗體
貨號：

CSB-PA606021ESR1HU
規格：

￥440
圖片：
Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA606021ESR1HU at dilution of 1:100

Immunohistochemistry of paraffin-embedded human endometrial cancer using CSB-PA606021ESR1HU at dilution of 1:100
其他：

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) PMPCA Polyclonal antibody
Uniprot No.：

Q10713
基因名：

PMPCA
別名：

1200002L24Rik antibody; 4933435E07Rik antibody; Alpha MPP antibody; Alpha-MPP antibody; FLJ26258 antibody; Inositol polyphosphate 5 phosphatase, 72 kD antibody; INPP5E antibody; KIAA0123 antibody; MGC104197 antibody; MGC93916 antibody; Mitochondrial matrix processing protease, alpha subunit antibody; mitochondrial processing peptidase subunit alpha antibody; Mitochondrial-processing peptidase subunit alpha antibody; MPPA_HUMAN antibody; P 55 antibody; P-55 antibody; Peptidase (mitochondrial processing) alpha antibody; pmpca antibody; RP11-413M3.1 antibody; RP23-306D20.8 antibody; SCAR2 antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Mitochondrial-processing peptidase subunit alpha protein (456-525AA)
免疫原種屬：

Homo sapiens (Human)
標記方式：

Non-conjugated
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

Antigen Affinity Purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
產品提供形式：

Liquid
應用范圍：

ELISA, IHC

推薦稀釋比：

Application	Recommended Dilution
IHC	1:20-1:200

Protocols：

ELISA Protocol
Immunohistochemistry (IHC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Substrate recognition and binding subunit of the essential mitochondrial processing protease (MPP), which cleaves the mitochondrial sequence off newly imported precursors proteins.
基因功能參考文獻：
1. study represents the first time that defects in PMPCA and mitochondrial processing peptidase have been described in association with a disease phenotype in humans. PMID: 25808372
2. OxLDL triggers retrograde translocation of arginase2 in aortic endothelial cells via ROCK and mitochondrial processing peptidase. PMID: 24903103
相關疾病：

Spinocerebellar ataxia, autosomal recessive, 2 (SCAR2)
亞細胞定位：

Mitochondrion matrix. Mitochondrion inner membrane.
蛋白家族：

Peptidase M16 family
組織特異性：

Ubiquitously expressed with highest expression in fetal tissues and adult brain, cerebellum and cerebellar vermis.
數據庫鏈接：

HGNC: 18667

OMIM: 213200

KEGG: hsa:23203

STRING: 9606.ENSP00000360782

UniGene: Hs.495471

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